Results 81 to 90 of about 4,995,654 (311)

A prospective cohort observational study investigating the association between the United Kingdom digital dermatitis genetic index and the disease prevalence in a population of Holstein heifers

Journal of Dairy Science
: The digital dermatitis index (DDI), a genetic index for digital dermatitis (DD) resistance has been previously associated with presence of DD in Holstein cows.
Alkiviadis Anagnostopoulos, Matthew Barden, Lara Robinson, Nektarios Siachos, Ana Sato, Kaixin Bao, Evangelos Lamprou, Amy Gillespie, Androniki Psifidi, Georgios Banos, Georgios Oikonomou   +10 more
doaj   +1 more source

Reaction of common bean genotypes to the reproduction of Meloidogyne javanica and Meloidogyne incognita

Pesquisa Agropecuária Tropical, 2019
The production of common bean (Phaseolus vulgaris L.) may be compromised by a variety of pests and diseases, with root-knot nematodes standing out among the soil-borne pathogens that cause significant losses.
João Pedro Gomes da Costa, Pedro Luiz Martins Soares, Roberta Luiza Vidal, Daniel Dalvan do Nascimento, Rivanildo Ferreira Junior   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Prospects of genetic engineering for robust insect resistance [PDF]

, 2014
Secondary plant metabolites are potentially of great value for providing robust resistance in plants against insect pests. Such metabolites often comprise small lipophilic molecules (SLMs), and can be similar also in terms of activity to currently used ...
Birkett, M. A., Pickett, J. A., Pickett, John A, Birkett, Michael A, Pickett, John   +4 more
core   +1 more source

Histological and transcriptome analysis uncover a robust early PTI and ETI-associated immune response in Musa acuminata subsp. burmannica accession ‘Calcutta 4’ to Fusarium oxysporum f. sp. cubense Subtropical Race 4

Frontiers in Plant Science
IntroductionBanana (Musa spp.) is a globally significant crop and a staple food in the diet of millions of people. However, commercial cultivars are highly susceptible to Fusarium wilt, a devastating disease caused by Fusarium oxysporum f. sp.
Érica de Castro Costa, Lucas Santos Bastos, Andresa Priscila de Souza Ramos, Leandro de Souza Rocha, Edson Perito Amorim, Claudia Fortes Ferreira, Nicola Vergara Lopes Serão, Roberto Coiti Togawa, Priscila Grynberg, Robert Neil Gerard Miller   +9 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Cereal Root Interactions with Soilborne Pathogens—From Trait to Gene and Back

Agronomy, 2019
Realizing the yield potential of crop plants in the presence of shifting pathogen populations, soil quality, rainfall, and other agro-environmental variables remains a challenge for growers and breeders worldwide.
Patricia A. Okubara, Amy B. Peetz, Richard M. Sharpe   +2 more
doaj   +1 more source

Toward a genetics of cancer resistance [PDF]

Proceedings of the National Academy of Sciences, 2009
Two of three humans never get cancer. Even the majority of heavy smokers remain cancer free. Is this a matter of chance, or are there cancer-resistant genotypes? Based on the evidence discussed, it would appear that evolution has favored a limited number of relatively common resistance genes that may nip incipient cancerous foci in the bud, i.e., to ...
openaire   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Population genetic analysis of Plasmodium falciparum parasites using a customized Illumina GoldenGate genotyping assay. [PDF]

, 2011
The diversity in the Plasmodium falciparum genome can be used to explore parasite population dynamics, with practical applications to malaria control.
Abdoulaye Djimde, Newbold, CI, Steven M Kiara, MacInnis, B, Jiang Hongying, Amaratunga, Chanaki, Mangano Valentina, Panos Deloukas, Socheat, Duong, Kirk Rockett, Jiang, H, Kivinen, K, MacInnis Bronwyn, Borrmann Steffen, Kwiatkowski, DP, Kiara Steven M., Kwiatkowski, Dominic, Pascal Michon, Valentina Mangano, Dominic P Kwiatkowski, Kwiatkowski Dominic P., Taane G Clark, Djimde Abdoulaye, Christopher I. Newbold, Borrmann, S, Deloukas, P, Rockett, K, Su, X-Z, Dominic P. Kwiatkowski, Nicholas J White, Imwong, Mallika, Ouedraogo, JB, Anderson, Timothy, Nicholas J. White, White Nicholas J., Zongo Issaka, Campino, S, Taane G. Clark, MacInnis, Bronwyn, Auburn Sarah, Clark, Taane G, Clark, TG, Newbold, Christopher, Nosten, François, Issaka Zongo, Nzila, A, Rockett Kirk, Gwilliam Rhian, Kevin Marsh, Djimde, Abdoulaye, Newbold, Christopher I, Xin-Zhuan Su, Kivinen, Katja, Amaratunga Chanaki, Rhian Gwilliam, Nosten François, Susana Campino, White, Nicholas J, Sarah Auburn, Fairhurst, Rick M, Michon, P, Nzila, Alexis, Gwilliam, Rhian, Mueller, Ivo, Siba, P, Doumbo Ogobara K., Ivo Mueller, Marsh, K, Zongo, Issaka, Chanaki Amaratunga, Timothy Anderson, Christopher I Newbold, Imwong Mallika, Jean-Bosco Ouedraogo, Clark Taane G., Alexis Nzila, Socheat Duong, Imwong, M, Anderson, T, Kiara, SM, White, NJ, Marsh, Kevin, Jean Bosco Ouedraogo, Fairhurst, RM, Steven M. Kiara, Michon, Pascal, Doumbo, Ogobara K, Deloukas, Panos, Marsh Kevin, Su, Xin-Zhuan, Djimde, A, Peter Siba, Siba, Peter, Mueller, I, Mallika Imwong, Ogobara K. Doumbo, Anderson Timothy, Hongying Jiang, White, Nicholas, Gwilliam, R, Katja Kivinen, Kiara, Steven M, Michon Pascal, Mangano, V, Siba Peter, Kivinen Katja, Zongo, I, Mueller Ivo, Campino Susana, Rick M. Fairhurst, Amaratunga, C, Newbold Christopher I., Auburn, Sarah, Xin Zhuan Su, Auburn, S, Rockett, Kirk, Bronwyn Macinnis, Nzila Alexis, Duong Socheat, François Nosten, Nosten, F, Su, XZ, Ouedraogo Jean-Bosco, Ouedraogo, J-B, Ogobara K Doumbo, Campino, Susana, Socheat, D, Jiang, Hongying, Doumbo, OK, Su Xin-Zhuan, Mangano, Valentina, Rick M Fairhurst, Ouedraogo, Jean-Bosco, Fairhurst Rick M., Borrmann, Steffen, Steffen Borrmann, Deloukas Panos, Kwiatkowski, Dominic P   +137 more
core   +1 more source