Results 91 to 100 of about 2,212,354 (298)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Body conformation and robustness as potential frontiers in pasture-based beef cattle breeding: a narrative review

open access: yesFrontiers in Animal Science
As the demand for pasture-finished beef continues to grow, the importance of sustainably producing cattle under pasture-based systems has become increasingly evident.
Titus J. Zindove
doaj   +1 more source

Farm Level Economic Implications of Genetic Selection for Improving Milk Fat Composition [PDF]

open access: yes
The objective of the study was to assess the farm level economic implications of value-adding genetic selection strategies to improve milk fat composition. Selection based on a quantitative trait (ratio of total saturated to total unsaturated fatty acids
Bovenhuis, Henk   +5 more
core   +1 more source

Estimates of Genetic and Phenotypic Trends of Growth Traits in Bali Cattle [PDF]

open access: yes, 2012
The aim of this study was to estimate genetic and phenotypic trends for growth traits including birth (BW), weaning (WW) and yearling weight (YW) in Bali cattle.
Gunawan, A. (A)   +2 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Genetic linkage and natural selection [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2010
The prevalence of recombination in eukaryotes poses one of the most puzzling questions in biology. The most compelling general explanation is that recombination facilitates selection by breaking down the negative associations generated by random drift (i.e. Hill–Robertson interference, HRI). I classify the effects of HRI owing to: deleterious mutation,
openaire   +2 more sources

Putting Process and Product Conceptions of Natural Selection and Genetic Drift to the Test [PDF]

open access: yes, 2013
This paper argues for two claims. First, despite a persistent appearance to the contrary in the philosophy of biology literature, the question of whether natural selection and genetic drift should be defined as processes or as the products (or outcomes)
Pence, Charles H.
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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