Results 91 to 100 of about 1,655,249 (351)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

An investigation of genetic algorithm-based feature selection techniques applied to keystroke dynamics biometrics [PDF]

, 2019
Due to the continuous use of social networks, users can be vulnerable to online situations such as paedophilia treats. One of the ways to do the investigation of an alleged pedophile is to verify the legitimacy of the genre that it claims. One possible
Da Costa Abreu, Marjory, Lima do Nascimento, Tuany Mariah, Monteiro de Oliveira, Andrelyne Vitória, Oliveira, Laura   +3 more
core  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Isolating the Mutator Transposable Element Insertional Mutant Gene mio16 of Maize Using Double Selected Amplification of Insertion Flanking Fragments (DSAIFF)

Journal of Integrative Agriculture, 2012
Mutator transposable element (Mu) has been used as an effective tool to clone maize (Zea mays L.) genes. One opaque endosperm mutant (mio16) was identified in a pool of Mu inserted mutants.
Wen-juan ZHONG, Mei-dong ZHANG, Liu-qi YANG, Ming-chun WANG, Yong-lian ZHENG, Wen-peng YANG, You-jun GAO   +6 more
doaj  

Molecular Genetic Techniques for the Proteoglycan Functions in Drosophila. [PDF]

Methods Mol Biol, 2022
Bowden N, Takemura M, Nakato H.
europepmc   +1 more source

Mobile transporter path planning [PDF]

The use of a genetic algorithm (GA) for solving the mobile transporter path planning problem is investigated. The mobile transporter is a traveling robotic vehicle proposed for the space station which must be able to reach any point of the structure ...
Baffes, Paul, Wang, Lui
core   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Integrated Management of Water, Nitrogen, and Genotype Selection for Enhanced Wheat Productivity in Moroccan Arid and Semi-Arid Regions

Agronomy
Bread wheat (Triticum aestivum L.) is essential global nutrition as it provides calories and protein. This study explored the impact of irrigation, environmental factors, nitrogen fertilization, and genotype selection on yield.
Ilham Khlila, Aziz Baidani, Oussama Hnizil, Ali Amamou   +3 more
doaj   +1 more source

Molecular Genetic Techniques in Biomarker Analysis Relevant for Drugs Centrally Approved in Europe. [PDF]

Mol Diagn Ther, 2022
Huebner T, Steffens M, Scholl C.
europepmc   +1 more source

Meta-Genetic Programming: Co-evolving the Operators of Variation [PDF]

, 2001
The standard Genetic Programming approach is augmented by co-evolving the genetic operators. To do this the operators are coded as trees of indefinite length.
Edmonds, Bruce
core