Results 161 to 170 of about 1,532,404 (358)

Genetic characterization of rebounding HIV-1 after cessation of highly active antiretroviral therapy [PDF]

, 2000
Linqi Zhang, Chris Chung, Bor-Shen Hu, He Tian, Yong Guo, Alexandria J. Kim, Eva Skulsky, Xia Jin, Arlene Hurley, Bharat Ramratnam, Martin Markowitz, David D. Ho   +11 more
openalex   +1 more source

Optimization Aspects of Carcinogenesis

, 2009
Any process in which competing solutions replicate with errors and numbers of their copies depend on their respective fitnesses is the evolutionary optimization process.
Brutovsky, B., Horvath, D.
core   +3 more sources

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Genetic and immunological therapy for cancer [PDF]

Journal of the Royal Society of Medicine, 2000
David J. Kerr, Annie M. Young
openaire   +3 more sources

Tumor necrosis factor and lymphotoxin-alpha genetic polymorphisms and risk of relapse in childhood B-cell precursor acute lymphoblastic leukemia: a case-control study of patients treated with BFM therapy [PDF]

, 2001
Martin Stanulla, André Schrauder, Karl Welte, Martin Schrappe   +3 more
openalex   +1 more source

Webcast courses in Medical Genetics and next generation sequencing [PDF]

, 2013
The European School of Genetic Medicine organised the 26th Course in Medical Genetics and the 2nd Course in Next Generation Sequencing, between the 12th and 20th May 2013.
Borg, Isabella
core  

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

LATEST ADVANCES FOR TREATING CONGENITAL ADRENAL HYPERPLASIA DUE TO 21-HYDROXYLASE DEFICIENCY

İstanbul Tıp Fakültesi Dergisi
Congenital adrenal hyperplasia (CAH) is a group of inherit ed diseases characterised by disrupted glucocorticoid (GC) and mineralocorticoid (MC) synthesis in the adrenal glands.
Ecesu Çetin, Mehmet Furkan Burak
doaj   +1 more source

Significance of genetic abnormalities after photodynamic therapy [PDF]

, 2001
Rebecca C. Fitzgerald, Laurence Lovat
openalex   +1 more source