Results 161 to 170 of about 8,605,496 (403)

Structured Psychosocial Stress and Therapeutic Intervention: Toward a Realistic Biological Medicine [PDF]

, 2003
Using generalized 'language of thought' arguments appropriate to interacting cognitive modules, we explore how disease states can interact with medical treatment, including, but not limited to, drug therapy.
Wallace, Rodrick
core  

92. Genetic Correction of Induced Pluripotent Stem Cells From Osteopetrotic Mice and Differentiation To the Hematopoietic Lineage as a Cell Therapy Approach [PDF]

, 2014

openalex   +1 more source

Genetic screening in new onset inflammatory bowel disease during anti-interleukin 17 therapy: unmet needs and call for action [PDF]

, 2021
Carlo Alberto Maronese, Enrico Zelin, Chiara Moltrasio, Giovanni Genovese, Angelo Valerio Marzano   +4 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction

, 2022
Stella Trompet, Iris Postmus, Helen R. Warren, Raymond Noordam, Roelof A. J. Smit, Elizabeth Theusch, Xiaohui Li, Benoît J. Arsenault, Daniel I. Chasman, G. A. Hitman, Patricia B. Munroe, Jerome I. Rotter, Bruce M. Psaty, Mark J. Caulfield, Ron M. Krauss, L. Adrienne Cupples, J. Wouter Jukema   +16 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

LATEST ADVANCES FOR TREATING CONGENITAL ADRENAL HYPERPLASIA DUE TO 21-HYDROXYLASE DEFICIENCY

İstanbul Tıp Fakültesi Dergisi
Congenital adrenal hyperplasia (CAH) is a group of inherit ed diseases characterised by disrupted glucocorticoid (GC) and mineralocorticoid (MC) synthesis in the adrenal glands.
Ecesu Çetin, Mehmet Furkan Burak
doaj   +1 more source

Genetic Predictors of Long-Term Response to Growth Hormone (GH) Therapy in Children With GH Deficiency and Turner Syndrome: The Influence of a SOCS2 Polymorphism [PDF]

, 2014
Adriana F. Braz, Everlayny F. Costalonga, Ericka Barbosa Trarbach, Renata C. Scalco, Alexsandra C. Malaquias, Gil Guerra‐Júnior, Sonir Roberto Rauber Antonini, Berenice B. Mendonça, Ivo J.P. Arnhold, Alexander A.L. Jorge   +9 more
openalex   +1 more source

Author response for "Genetic risk of hyperuricemia in hypertensive patients associated with antihypertensive drug therapy: a longitudinal study"

, 2021
Yu Chen, Yunyun Yang, Yixuan Zhong, Jian Li, Tao Kong, Shuyuan Zhang, Shujun Yang, Cunjin Wu, Bing Cui, Li Fu, Rutai Hui, Weili Zhang   +11 more
openalex   +1 more source