Results 181 to 190 of about 8,605,496 (403)

Therapeutic future of Fuchs endothelial corneal dystrophy: An ongoing way to explore

Taiwan Journal of Ophthalmology
Fuchs endothelial corneal dystrophy (FECD) is one of the most common corneal diseases that causes loss of visual acuity in the world. FECD is a genetically and pathogenetically heterogeneous disease that results in the failure of corneal endothelial ...
Jia-Xin Liu, Tung-Lin Chiang, Kai-Feng Hung, Yi-Chen Sun   +3 more
doaj   +1 more source

Genetically modified IFN-alpha for gene therapy treatment of squamous cell carcinoma

, 2006
Ryan Craig
openalex   +2 more sources

Rare genetic forms of obesity: From gene to therapy

, 2020
Karine Clément, Héléna Mosbah, Christine Poitou   +2 more
openalex   +2 more sources

Genetic Analysis and Targeted Therapy Using Buparlisib and MK2206 in a Patient with Triple Metachronous Cancers of the Kidney, Prostate, and Squamous Cell Carcinoma of the Lung: A Case Report

, 2021
Tong Zhao, Yuqin Tian, Xinjia Ding, Lin Liu, Bowen Tan, Bin Yang, Jianlin Wu, Ting Lei, Ruoyu Wang, Yan Ding   +9 more
openalex   +2 more sources

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Multiple Myeloma : an update on disease biology and therapy [PDF]

, 2004
Multiple myeloma is a malignancy of immunoglobulin producing plasma cells. Clinical features include bone pain due to lytic bone lesions or pathological fractures, anemia, symptomatic hypercalcemia, renal insufficiency, recurrent infections and ...
Cook, Rachel J., Dingli, David
core  

Cas13b-mediated RNA targeted therapy alleviates genetic dilated cardiomyopathy in mice [PDF]

, 2023
Jiacheng Li, Xin Kuang, Yahuan Li, Hong Lian, Yu Nie   +4 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

KRONİK AĞRIDA GENETİK TEDAVİ VE HEMŞİRENİN ROLÜ

Sakarya Üniversitesi Holistik Sağlık Dergisi, 2019
Kronik ağrı, insidansı yüksek olan önemli sağlık sorunlarından biridir. Kronik ağrı bireyin yaşam kalitesini olumsuz etkilemekte, immun sistemi baskılama, anksiyete, depresyon ve intihara eğilim gibi ciddi komplikasyonlara yol açmaktadır.
Kübra Yılmaz, Sema Koçaşlı
doaj  

DNA as Patentable Subject Matter and a Narrow Framework for Addressing the Perceived Problems Caused by Gene Patents [PDF]

, 2011
Concerns about the alleged harmful effects of gene patents— including hindered research and innovation and impeded patient access to high-quality genetic diagnostic tests—have resulted in overreactions from the public and throughout the legal profession.
Schilling, Stephen H.
core   +1 more source