Results 261 to 270 of about 752,866 (297)
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Annual Review of Genetics, 1975
The introduction of a new organism into the repertoire of genetic tools is justified on the basis of its aptness for investigations of new problems, for new approaches to old problems, or for testing the relevance of principles discovered in phylo genetically distant groups. In this review many important publications must be omitted to provide for the
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The introduction of a new organism into the repertoire of genetic tools is justified on the basis of its aptness for investigations of new problems, for new approaches to old problems, or for testing the relevance of principles discovered in phylo genetically distant groups. In this review many important publications must be omitted to provide for the
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Surrogate Genetics: The Use of Bacterial Hybrids as a Genetic Tool
Methods, 2000Experimental dissection of bacterial genomes requires a well-developed set of genetic tools, but many bacteria lack the essential tools required for genetic analysis. Recombination of a region of chromosomal DNA from poorly characterized donor bacteria with the chromosome of a suitable surrogate host creates a genetically malleable hybrid, providing a ...
S, Maloy, T, Zahrt
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Computational Tools for Causal Inference in Genetics
Cold Spring Harbor Perspectives in Medicine, 2020The advent of large-scale, phenotypically rich, and readily accessible data provides an unprecedented opportunity for epidemiologists, statistical geneticists, bioinformaticians, and also behavioral and social scientists to investigate the causes and consequences of disease. Computational tools and resources are an integral component of such endeavors,
Tom G, Richardson +2 more
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1984
In the past ten years several advances in biotechnology have revolutionized the way fundamental biological problems are approached. I will discuss three of these relatively recently developed disciplines in biotechnology—recombinant DNA, microchemical instrumentation, and monoclonal antibodies—and I will point out the striking synergies that arise from
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In the past ten years several advances in biotechnology have revolutionized the way fundamental biological problems are approached. I will discuss three of these relatively recently developed disciplines in biotechnology—recombinant DNA, microchemical instrumentation, and monoclonal antibodies—and I will point out the striking synergies that arise from
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Transposable Bacteriophages as Genetic Tools
2017Phage Mu is the paradigm of a growing family of bacteriophages that infect a wide range of bacterial species and replicate their genome by replicative transposition. This molecular process, which is used by other mobile genetic elements to move within genomes, involves the profound rearrangement of the host genome [chromosome(s) and plasmid(s)] and can
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An educational genetic algorithms learning tool
IEEE Transactions on Education, 2001During the last thirty years, there has been a rapidly growing interest in a field called genetic algorithms (GAs). The field is at a stage of tremendous growth as evidenced by the increasing number of conferences, workshops and papers concerning it, as well as the emergence of a central journal for the field.
Ying-Hong Liao, Chuen-Tsai Sun
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Genetic Assembly Tools for Synthetic Biology
2011With the completion of myriad genome sequencing projects, genetic bioengineering has expanded into many applications including the integrated analysis of complex pathways, the construction of new biological parts and the redesign of existing, natural biological systems.
Billyana, Tsvetanova +11 more
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RNA Interference as a Genetic Tool in Trypanosomes
2008RNA interference (RNAi) is a cellular mechanism that is often exploited as a technique for quelling the expression of a specific gene. RNAi studies are carried out in vivo, making this a powerful means for the study of protein function in situ Several trypanosomatids, including those organisms responsible for human and animal diseases, naturally ...
Vivian, Bellofatto +1 more
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Population Genetic Tools: Application to Cancer
Seminars in Oncology, 2007The availability of a reference human genome sequence, an increasingly dense catalog, knowledge of common genetic variation, and new developments in technology present an unprecedented opportunity to systematically explore the genetic basis of complex human diseases such as cancer.
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Self‐Insurance With Genetic Testing Tools
Journal of Risk and Insurance, 2015AbstractThe development of genetic testing creates opportunities to better target disease prevention actions. In this article, we determine how the genetic information modifies self‐insurance efforts in different health insurance market equilibria with adverse selection.
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