Results 71 to 80 of about 5,564,571 (413)

Average fold-change of genetic pathways in biological transitions [PDF]

arXiv, 2023
A biological transition from a state N to a state T is characterized by a rearrangement of the gene expression profile in the system, quantitatively measured through the differential expression of genes. In contrast, changes in genetic pathways are usually evaluated by means of hypothesis testing schemes. We introduce a quantitative measure in order to
arxiv  

Landau Gauge Fixing supported by Genetic Algorithm [PDF]

, 1999
A class of algorithms for the Landau gauge fixing is proposed, which makes the steepest ascent (SA) method be more efficient by concepts of genetic algorithm.
Azusa Yamaguchi, Cucchieri, de Forcrand, Gribov, Hetrick, Hideo Nakajima, Mandula, Markham, Maskawa, Maskawa, Singer, Zwanziger, Zwanziger   +12 more
core   +2 more sources

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Factors influencing somatic embryogenesis, regeneration and Agrobacterium-mediated transformation of cassava (Manihot esculenta Crantz) cultivar TME14

Frontiers in Plant Science, 2015
Routine production of large numbers of transgenic plants is required to fully exploit advances in cassava biotechnology and support development of improved germplasm for deployment to farmers.
Evans Nyaega Nyaboga, Joshua Mugendi Njiru, Leena eTripathi   +2 more
doaj   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

Leaf rust resistance in wheat and interpretation of the antifungal activity of silver and copper nanoparticles

Scientific Reports
Wheat production is jeopardized by Puccinia triticina, the pathogen responsible for wheat leaf rust. This study assessed the impact of silver (Ag) and copper (Cu) nanoparticles (NPs) on the control of wheat leaf rust disease and the underlying mechanisms
Atwa A. Atwa, Shreen S. Ahmed, Gehan H. Abd El-Aziz, Mohamed A. Abou-Zeid, Reda I. Omara, Nourhan A. Atwa, Ashraf H. Fahmy   +6 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Genome-wide identification and evolutionary analysis of the AP2/EREBP, COX and LTP genes in Zea mays L. under drought stress

Scientific Reports
AP2 (APETALA2)/EREBP (ethylene-responsive element-binding protein), cytochrome c oxidase (COX) and nonspecific lipid transfer proteins (LTP) play important roles in the response to drought stress.
Amaal Maghraby, Mohamed Alzalaty
doaj   +1 more source

The Genetic Transformation of Chlamydia pneumoniae

Msphere, 2018
The absence of tools for the genetic manipulation of C. pneumoniae has hampered research into all aspects of its biology. In this study, we established a novel reproducible method for C. pneumoniae transformation based on a plasmid shuttle vector system.
K. Shima, Maximilian Wanker, R. Skilton, Lesley T. Cutcliffe, C. Schnee, T. Kohl, S. Niemann, Javier Geijo, M. Klinger, P. Timms, T. Rattei, K. Sachse, I. Clarke, J. Rupp   +13 more
semanticscholar   +1 more source

Significant variation in transformation frequency in Streptococcus pneumoniae [PDF]

, 2013
The naturally transformable bacterium Streptococcus pneumoniae is able to take up extracellular DNA and incorporate it into its genome. Maintaining natural transformation within a species requires that the benefits of transformation outweigh its costs ...
A Tomasz, A Tomasz, AM Whatmore, Benjamin A Evans, BJ Haijema, CG Dowson, CG Dowson, CS Wylie, D Bogaert, D Bogaert, Daniel E Rozen, DF Vestrheim, DL Wilson, E Libby, F Griffith, F Iannelli, G Pozzi, H Bernstein, H Maughan, H Steinmoen, HJ Beaumont, I Chen, I Mortier-Barriere, J Corander, J Majewski, J Majewski, J Sikorski, J Yang, JP Claverys, KL O'Brien, L Hadany, LS Havarstein, M Carrolo, M Prudhomme, M Travisano, M Vos, MC Enright, MC Enright, MG Lorenz, MJ Ferrandiz, ML Joloba, NJ Croucher, O Fujise, O Gutierrez, OE Cornejo, OT Avery, PJ Johnsen, RJ Redfield, RJ Redfield, RJ Redfield, S Schoustra, SA West, SN Peterson, SP Otto, WP Hanage, X Didelot, YC Hsieh   +56 more
core   +1 more source