Results 91 to 100 of about 566,900 (297)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

GROUPING OF CATINGUEIRA GENOTYPES BASED ON MORPHOLOGICAL CHARACTERISTICS

open access: yesRevista Árvore
The objective of this study was to obtain information about the characteristics of Poincianella pyramidalis (Tul.) through morphological characters. We have analyzed eleven genotypes of P.
Leonardo Silva Souza   +5 more
doaj   +1 more source

Study of genetic variability and correlation in interspecific derivatives of Pigeonpea [Cajanus cajan (L.) Millsp.] [PDF]

open access: yesElectronic Journal of Plant Breeding, 2010
Forty interspecific derivatives (ISD) of Pigeonpea along with five national checks derived from ICRISAT, Patancheru,Hyderabad and one local check were screened to study the extent of genetic variability for yield and yield contributingcharacter and their
S.S. Linge , H.V. Kalpande, S.L. Sawargaonkar, B.V. Hudge and H.P. Thanki
doaj  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Epidemiological support for genetic variability at hypothalamic–pituitary–adrenal axis and serotonergic system as risk factors for major depression

open access: yesNeuropsychiatric Disease and Treatment, 2015
Ana Ching-López,1 Jorge Cervilla,1–3 Margarita Rivera,1–3 Esther Molina,4 Kathryn McKenney,2 Isabel Ruiz-Perez,3,5,6 Miguel Rodríguez-Barranco,5 Blanca Gutiérrez1,21Department of Psychiatry, Institute of Neurosciences ...
Ching-López A   +7 more
doaj  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

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