Genetic variability of <i>HIF1A</i> and response to treatment with cisplatin in combination with pemetrexed or gemcitabine in patients with malignant mesothelioma. [PDF]
Setina M +5 more
europepmc +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Genetic variability, morphological diversity, and antioxidant potential in gynoecious Coccinia accessions: implications for breeding and biofortification. [PDF]
Yadav LP +13 more
europepmc +1 more source
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
<i>Toxoplasma gondii</i> seroprevalence, seroconversion rates and genetic variability in humans from Uruguay. [PDF]
Valentin-Decuadro A +11 more
europepmc +1 more source
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Optimizing the breeding strategy in Vanaraja female parent line chicken by monitoring the genetic variability for the major performance traits. [PDF]
Niranjan M +5 more
europepmc +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Genetic variability in physiological and agronomic traits of newly developed rice lines under well-watered and water-deficit conditions. [PDF]
Sakran RM +7 more
europepmc +1 more source

