In Greece, seven native horse breeds have been identified so far. Among these, the Skyros pony is outstanding through having a distinct phenotype. In the present study, the aim was to assess genetic diversity in this breed, by using different types of ...
Elisabeth Bömcke+2 more
doaj
Efficient Noisy Optimisation with the Sliding Window Compact Genetic Algorithm [PDF]
The compact genetic algorithm is an Estimation of Distribution Algorithm for binary optimisation problems. Unlike the standard Genetic Algorithm, no cross-over or mutation is involved. Instead, the compact Genetic Algorithm uses a virtual population represented as a probability distribution over the set of binary strings. At each optimisation iteration,
arxiv
Cellular deconvolution of GTEx tissues powers discovery of disease and cell-type associated regulatory variants. [PDF]
The Genotype-Tissue Expression (GTEx) resource has provided insights into the regulatory impact of genetic variation on gene expression across human tissues; however, thus far has not considered how variation acts at the resolution of the different cell ...
D'Antonio, Matteo+3 more
core
Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha+6 more
wiley +1 more source
Genetic variation between Colletotrichum lindemuthianum isolates
We characterized the genetic diversity of seventy-three C. lindemuthianum isolates collected from 10 different countries by Amplified Fragment Length Polymorphism (AFLP) analysis.
K.I. Ansari+5 more
doaj +1 more source
Natural selection. II. Developmental variability and evolutionary rate
In classical evolutionary theory, genetic variation provides the source of heritable phenotypic variation on which natural selection acts. Against this classical view, several theories have emphasized that developmental variability and learning enhance ...
Altschuler+57 more
core +2 more sources
GENETIC VARIATION IN AN ASEXUAL SPECIES, THE GARDEN STRAWBERRY [PDF]
R. E. Comstock+2 more
openalex +1 more source
A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini+11 more
wiley +1 more source
Phylogeny of the members of the genus Alburnoides in Iran using COI gene
Up to now, twelve species of the genus Alburnoides belonged to Cyprinidae have been described from Iranian inland water solely based on the morphological characteristics.
S. Eagderi; A. Jouladeh-Roudbar; J. Imani Harsini; M. Rostami
doaj
Exploring the genetic patterns of complex diseases via the integrative genome-wide approach [PDF]
Motivation: Genome-wide association studies (GWASs), which assay more than a million single nucleotide polymorphisms (SNPs) in thousands of individuals, have been widely used to identify genetic risk variants for complex diseases. However, most of the variants that have been identified contribute relatively small increments of risk and only explain a ...
arxiv