Results 251 to 260 of about 2,029,300 (329)

A gene-based model of fitness and its implications for genetic variation: genetic and inbreeding loads. [PDF]

Genetics
Johri P, Charlesworth B.
europepmc   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Language Modelling Techniques for Analysing the Impact of Human Genetic Variation. [PDF]

Bioinform Biol Insights
Hegde M, Nebel JC, Rahman F.
europepmc   +1 more source

Effect of The Pfizer-Biontech Vaccine on Ifn-Γ Serum Levels and its Genetic Variations in Response to Vaccination

Radhia Hussain Fade, Mohemed Fleeh Dareef, Salah Mehdi Medical Microbiology   +2 more
openalex   +2 more sources

Genetic variation in N-acetyltransferases 1 and 2, cigarette smoking, and risk of non-Hodgkin lymphoma

, 2009
Briseis A. Kilfoy, Tongzhang Zheng, Qing Lan, Xuesong Han, Theodore R. Holford, David W. Hein, Qin Qin, Brian P. Leaderer, Lindsay M. Morton, Meredith Yeager, Peter Boyle, Ping Zhao, Stephen J. Chanock, Nathaniel Rothman, Yawei Zhang   +14 more
openalex   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Genetic variation and genome-enabled selection of white lupin for key seed quality traits. [PDF]

BMC Genomics
Annicchiarico P, Osorio C, Nazzicari N, Ferrari B, Barzaghi S, Biazzi E, Tava A, Pecetti L, Notario T, Romani M, Crosta M.   +10 more
europepmc   +1 more source

Assessment of genetic variations in micropropagated plants of Nepenthes khasiana Hook f, an endemic insectivorous plant of Meghalaya

, 2014
Soibam Purnima Devi
openalex   +1 more source

Genetic variation among quince (Cydonia oblonga Mill.) genotypes sampled from the Coruh valley in Turkey

, 2014
Emine Orhan, Gokce Nardemir, Güleray Ağar, Sezai Erċışlı   +3 more
openalex   +1 more source

Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein

FEBS Open Bio, EarlyView.
This research protocol offers a guide for the cloning, expression, and purification of the Chandipura virus matrix protein using E. coli. It also includes a step‐by‐step procedure for cloning, expressing, and conducting fluorescence imaging of GFP‐fused Chandipura virus matrix protein in mammalian cell lines.
Mariana Grieben
wiley   +1 more source