Results 251 to 260 of about 4,640,461 (294)
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Theophylline metabolism: Variation and genetics
Clinical Pharmacology and Therapeutics, 1984Variation of theophylline metabolism in 54 healthy, nonmedicated adults (13 monozygotic [MZ] twin pairs, 11 dizygotic [DZ] twin pairs, and 6 single individuals) was assessed by kinetic study. Elimination rate constant, clearance (Cl), t1/2, and apparent volume of distribution, as well as urine excretion of unchanged theophylline and of the three major ...
Miller, Marvin E. +3 more
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Genetic Variations and Association
2010Publisher Summary This chapter provides information about the human hydroxytryptamine (HT)R6 gene structure, its evolution, and its expression profile in both the brain and in peripheral tissues. The chapter describes the regulatory regions like binding sites for transcription factors (TFs) or for miRNA.
GENNARELLI, Massimo, CATTANEO, Annamaria
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Genetic variation in prehistoric Sardinia
Human Genetics, 2007We sampled teeth from 53 ancient Sardinian (Nuragic) individuals who lived in the Late Bronze Age and Iron Age, between 3,430 and 2,700 years ago. After eliminating the samples that, in preliminary biochemical tests, did not show a high probability to yield reproducible results, we obtained 23 sequences of the mitochondrial DNA control region, which ...
CARAMELLI, DAVID +14 more
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2006
Abstract Genetic variation provides the underpinning of modern biological thought. From evolutionary biologists studying finches in the field, to drug development in the pharmaceutical industry; from the developmental geneticists trying to understand the body plan of a mouse, to the researchers investigating the genetic basis for ...
Marta L Wayne, Michael M Miyamoto
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Abstract Genetic variation provides the underpinning of modern biological thought. From evolutionary biologists studying finches in the field, to drug development in the pharmaceutical industry; from the developmental geneticists trying to understand the body plan of a mouse, to the researchers investigating the genetic basis for ...
Marta L Wayne, Michael M Miyamoto
openaire +2 more sources
Genetic testing in prostate cancer management: Considerations informing primary care
Ca-A Cancer Journal for Clinicians, 2022Mary-Ellen Taplin +2 more
exaly
Cryptic genetic variation: evolution's hidden substrate
Nature Reviews Genetics, 2014Matthew Rockman, Annalise Paaby
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