Results 81 to 90 of about 895,195 (259)

Genetic variation between Colletotrichum lindemuthianum isolates

Plant Protection Science, 2002
We characterized the genetic diversity of seventy-three C. lindemuthianum isolates collected from 10 different countries by Amplified Fragment Length Polymorphism (AFLP) analysis.
K.I. Ansari, N. Palacios, C. Araya, T. Langin, D. Egan, F.M. Doohan   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Phylogeny of the members of the genus Alburnoides in Iran using COI gene

‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 2019
Up to now, twelve species of the genus Alburnoides belonged to Cyprinidae have been described from Iranian inland water solely based on the morphological characteristics.
S. Eagderi; A. Jouladeh-Roudbar; J. Imani Harsini; M. Rostami
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Overcoming maladaptive plasticity through plastic compensation

Current Zoology, 2013
Most species evolve within fluctuating environments, and have developed adaptations to meet the challenges posed by environmental heterogeneity. One such adaptation is phenotypic plasticity, or the ability of a single genotype to produce multiple ...
Matthew R.J. MORRIS, Sean M. ROGERS
doaj  

Identifying Genetic Variants in Patients With Cefaclor‐Induced Anaphylaxis Using Human Leukocyte Antigen Typing and Whole‐Exome Sequencing

Clinical and Translational Allergy
Background Cefaclor is a commonly prescribed β‐lactam antibiotic and a known major cause of immediate‐type drug hypersensitivity in Korea. However, its genetic risk factors remain poorly understood.
Sung‐Ryeol Kim, Da Eun Lee, Hyun Young Jung, In‐Wha Kim, Hye‐Ryun Kang, Kyung Hee Park, Jung‐Won Park, Jung‐Mi Oh, Jae‐Hyun Lee   +8 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source