Results 41 to 50 of about 634,337 (325)
A test problem for visual investigation of high-dimensional multi-objective search [PDF]
, 2014 An inherent problem in multiobjective optimization is that the visual observation of solution vectors with four or more objectives is infeasible, which brings major difficulties for algorithmic design, examination, and development.
Miqing Li +5 more
core +4 more sources
Use of herpes virus amplicon vectors to study brain disorders
BioTechniques, 2005 There is an enormous initiative to establish the genetic basis for disorders of brain function. Unfortunately, genetic intervention is not accomplished easily in the nervous system.
Rachael L. Neve +3 more
doaj +1 more source
Journal of Biomedical Science, 2022 Viruses are naturally endowed with the capacity to transfer genetic material between cells. Following early skepticism, engineered viruses have been used to transfer genetic information into thousands of patients, and genetic therapies are currently ...
Jonas Holst Wolff, Jacob Giehm Mikkelsen
doaj +1 more source
Vector-based genetically modified vaccines: Exploiting Jenner’s legacy
Vaccine, 2016 The global vaccine market is diverse while facing a plethora of novel developments. Genetic modification (GM) techniques facilitate the design of 'smarter' vaccines. For many of the major infectious diseases of humans, like AIDS and malaria, but also for most human neoplastic disorders, still no vaccines are available.
Ramezanpour, Bahar +3 more
openaire +3 more sources
Geminiviruses and their application in biotechnology
Journal of Integrative Agriculture, 2017 Being a major class of single-stranded DNA viruses, geminiviruses are mostly studied due to their catastrophic infectious effect on crops. These DNA viruses are characteristic for their ability in quickly multiplying viral genetic materials without ...
Qiu-ying YANG, Bo DING, Xue-ping ZHOU
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Genetic Manipulation of Ticks: A Paradigm Shift in Tick and Tick-Borne Diseases Research
Frontiers in Cellular and Infection Microbiology, 2021 Ticks are obligate hematophagous arthropods that are distributed worldwide and are one of the most important vectors of pathogens affecting humans and animals.
Andrew Nuss +3 more
doaj +1 more source
A method for generating realistic correlation matrices [PDF]
, 2013 Simulating sample correlation matrices is important in many areas of statistics. Approaches such as generating Gaussian data and finding their sample correlation matrix or generating random uniform $[-1,1]$ deviates as pairwise correlations both have ...
Garcia, Stephan Ramon +2 more
core +5 more sources
Malaria Control with Genetically Manipulated Insect Vectors
Science, 2002 At a recent workshop, experts discussed the benefits, risks, and research priorities associated with using genetically manipulated insects in the control of vector-borne diseases.
Alphey L. +22 more
openaire +4 more sources
BioTechniques, 2006 Integrative, centromeric, and episomal plasmids are essential for easy, fast, and reliable genetic manipulation of yeast. We constructed a system of shuttle vectors based on the widely used plasmids of the pRS series.
Christof Taxis, Michael Knop
doaj +1 more source
Simulating population genetics of pathogen vectors in changing landscapes: guidelines and application with Triatoma brasiliensis. [PDF]
PLoS Neglected Tropical Diseases, 2014 BACKGROUND:Understanding the mechanisms that influence the population dynamics and spatial genetic structure of the vectors of pathogens infecting humans is a central issue in tropical epidemiology.
Francois Rebaudo +5 more
doaj +1 more source