Results 41 to 50 of about 4,360,463 (355)
Simulating population genetics of pathogen vectors in changing landscapes: guidelines and application with Triatoma brasiliensis. [PDF]
PLoS Neglected Tropical Diseases, 2014 BACKGROUND:Understanding the mechanisms that influence the population dynamics and spatial genetic structure of the vectors of pathogens infecting humans is a central issue in tropical epidemiology.
Francois Rebaudo +5 more
doaj +1 more source
Genetics of Major Insect Vectors
, 2011 Publisher Summary Vector-borne diseases are responsible for a substantial portion of the global disease. Control of insect vectors is often the best and sometimes the only way to protect the population from these destructive diseases. This chapter reviews vector genetics of three of the most important vector-borne diseases that have much to contribute
Dorn, P.L. +4 more
openaire +3 more sources
Genetic modification of baculovirus expression vectors
Virologica Sinica, 2012 As a protein expression vector, the baculovirus demonstrates many advantages over other vectors. With the development of biotechnology, baculoviral vectors have been genetically modified to facilitate high level expression of heterologous proteins in both insect and mammalian cells.
Shufen Li +3 more
openaire +3 more sources
BioTechniques, 2006 Integrative, centromeric, and episomal plasmids are essential for easy, fast, and reliable genetic manipulation of yeast. We constructed a system of shuttle vectors based on the widely used plasmids of the pRS series.
Christof Taxis, Michael Knop
doaj +1 more source
Continuous multilinguality with language vectors [PDF]
Conference of the European Chapter of the Association for Computational Linguistics, 2016 Most existing models for multilingual natural language processing (NLP) treat language as a discrete category, and make predictions for either one language or the other. In contrast, we propose using continuous vector representations of language. We show
Robert Östling, J. Tiedemann
semanticscholar +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
mBio, 2020 Red blood cell (RBC) invasion by Plasmodium merozoites requires multiple steps that are regulated by signaling pathways. Exposure of P. falciparum merozoites to the physiological signal of low K+, as found in blood plasma, leads to a rise in cytosolic ...
Kunal R. More +13 more
doaj +1 more source
A CRISPR-Cas9 System for Genetic Engineering of Filamentous Fungi
PLoS ONE, 2015 The number of fully sequenced fungal genomes is rapidly increasing. Since genetic tools are poorly developed for most filamentous fungi, it is currently difficult to employ genetic engineering for understanding the biology of these fungi and to fully ...
C. S. Nødvig +3 more
semanticscholar +1 more source
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source
Vectors for Glioblastoma Gene Therapy: Viral & Non-Viral Delivery Strategies
Nanomaterials, 2019 Glioblastoma multiforme is the most common and aggressive primary brain tumor. Even with aggressive treatment including surgical resection, radiation, and chemotherapy, patient outcomes remain poor, with five-year survival rates at only 10%.
Breanne Caffery +2 more
semanticscholar +1 more source