Results 21 to 30 of about 3,096,858 (303)
Degeneration of Bioprosthetic Heart Valves: Update 2020
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020 The implantation of bioprosthetic heart valves (BHVs) is increasingly becoming the treatment of choice in patients requiring heart valve replacement surgery.
Alexander E. Kostyunin +5 more
doaj +1 more source
Immunotoxicological Evaluation of Genetically Modified Rice Expressing Cry1Ab/Ac Protein (TT51-1) by a 6-Month Feeding Study on Cynomolgus Monkeys. [PDF]
PLoS ONE, 2016 The present study was performed to evaluate the food safety of TT51-1, a new type of genetically modified rice that expresses the Cry1Ab/Ac protein (Bt toxin) and is highly resistant to most lepidopteran pests.
Xiaoyan Tan +11 more
doaj +1 more source
Welfare Issues of Genetically Modified Animals [PDF]
ILAR Journal, 2002 Genetically engineered animals have opened new frontiers in the study of physiology and disease processes. Mutant animals offer more accurate disease models and increased precision for pathogenesis and treatment studies. Their use offers hope for improved therapy to patients with conditions that currently have poor or ineffective treatments.
openaire +2 more sources
Danos oxidativos e neurodegeneração: o quê aprendemos com animais transgênicos e nocautes?
Química Nova, 2006 Accumulated evidence indicates that oxidative stress plays a role in neurodegenerative diseases, such as Alzheimer, Parkinson and Amyotrophic Lateral Sclerosis.
Lívea Fujita Barbosa +2 more
doaj +1 more source
Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2019 Rat line lacking the dopamine transporter (DAT-KO rats) was recently developed. Lack of DAT in these mutants manifests behaviorally as spontaneous hyperactivity and cognitive deficits.
I. Sukhanov +5 more
doaj +1 more source
Annals of Agricultural and Environmental Medicine, 2017 Introduction Agriculture based on genetically modified organisms plays an increasingly important role in feeding the world population, which is evidenced by a considerable growth in the size of land under genetically modified crops (GM).
Stanisław Lachowski +5 more
doaj +1 more source
The effects of tail biopsy for genotyping on behavioral responses to nociceptive stimuli. [PDF]
PLoS ONE, 2009 Removal of a small segment of tail at weaning is a common method used to obtain tissue for the isolation of genomic DNA to identify genetically modified mice.
Maria Elena P Morales, Robert W Gereau
doaj +1 more source
Journal of Animal Reproduction and Biotechnology, 2018 Pigs are considered as optimal donor animal for the successful xenotransplantation. To increase the possibility of clinical application, genetic modification to increase compatibility with human is an important and essential process. Genetic modification
Bumrae Cho +7 more
doaj +1 more source
Simple Genome Editing of Rodent Intact Embryos by Electroporation. [PDF]
PLoS ONE, 2015 The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated (Cas) system is a powerful tool for genome editing in animals. Recently, new technology has been developed to genetically modify animals without using highly skilled ...
Takehito Kaneko, Tomoji Mashimo
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh +4 more
wiley +1 more source