Are good ideas enough?: The impact of socio-economic and regulatory factors on GMO commercialisation
Biological Research, 2013 In recent years scientific literature has seen an increase in publications describing new transgenic applications. Although technically-sound, these promising developments might not necessarily translate into products available to the consumer.
Núria Vàzquez-Salat
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
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Pharmaceutical and Industrial Traits in Genetically Modified Crops: Co-existence with Conventional Agriculture, August 2006 [PDF]
, 2006 This paper discusses the implications of using genetically modified crops to biomanufacture pharmaceuticals and industrial compounds from the perspective of their co-existence with conventional agriculture. Such plant-made pharmaceuticals and plantmade
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Efficient In Vivo Introduction of Point Mutations Using ssODN and a Co-CRISPR Approach
Biological Procedures Online, 2020 Background The generation of point mutations is a major tool for evaluating the roles of specific nucleotides or amino acids within the regulatory or functional landscape. However, examination of these mutations in vivo requires the generation of animals
Tgst Levi +4 more
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Genetically Modified Rabbits for Cardiovascular Research
Frontiers in Genetics, 2021 Rabbits are one of the most used experimental animals for investigating the mechanisms of human cardiovascular disease and lipid metabolism because they are phylogenetically closer to human than rodents (mice and rats).
Jianglin Fan +4 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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Post market environmental monitoring of genetically modified herbicide tolerant crops (Working group report from the 4th international workshop on PMEM of genetically modified plants, Quedlinburg, Germany 2010) [PDF]
, 2011 According to European Union (EU) legislation, genetically modified (GM) crops released for commercial cultivation have to be monitored. Here we summarise the discussion of a working group that convened during the 4th International Workshop on Post Market
D. Bartsch +8 more
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Neural circuits mediating olfactory-driven behavior in fish
Frontiers in Neural Circuits, 2013 The fish olfactory system processes odor signals and mediates behaviors that are crucial for survival such as foraging, courtship and alarm response. Although the upstream olfactory brain areas (olfactory epithelium and olfactory bulb) are well studied ...
Florence eKermen +9 more
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Recent Advances in Genetically Engineered Microorganisms and their Risks: A Review
International Journal on Food, Agriculture and Natural Resources, 2023 Genetically engineered microorganisms have applications in various domains, such as agriculture, bioscience, healthcare, life sciences, and research. The novel methods of the system Clustered Regularly Interspaced Short Palindromic Repeats associated ...
Jiregna Gari +2 more
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FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
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