Results 121 to 130 of about 54,452 (291)
Advanced Materials Technologies, EarlyView.The hydroporator platform employs controlled hydrodynamic deformation for efficient mRNA and CRISPR/Cas9 delivery into primary human T cells, enabling allogeneic CAR‐T cell manufacturing. It preserves cell functionality and drives potent gene editing, CAR expression, and tumor cytotoxicity, while feature‐based analysis links these functional outcomes ...
Soohyun Jeon +6 more
wiley +1 more source
EFSA Journal, 2019 Following the submission of application EFSA‐GMO‐RX‐015 under Regulation (EC) No 1829/2003 from Bayer Agriculture BVBA, the EFSA Panel on Genetically Modified Organisms (GMO Panel) was asked to deliver a scientific risk assessment on the data submitted ...
EFSA Panel on Genetically Modified Organisms (GMO) +19 more
doaj +1 more source
Safety Assessment RP652 Genetically Modified MIR162 Maize
FSA Research and Evidence“Following the submission of application RP652 to the Food Standards Agency (FSA) under assimilated Regulation (EC) No. 1829/2003 from Syngenta Crop Protection NV/SA, represented by Syngenta Limited (Bracknell, UK), FSA/FSS (Food Standards Scotland) have undertaken a safety assessment on genetically modified MIR162 maize.
openaire +1 more source
IL‐3 Modulates Microglia Polarization and Attenuates Neuroinflammation in Traumatic Brain Injury
Advanced Science, EarlyView.IL‐3 recruits PRDX1 through IL‐3R to modulate the inflammatory response of microglia via the KEAP1‐NRF2‐HO‐1/NF‐κB pathway to attenuate neuroinflammation in traumatic brain injury. ABSTRACT Microglia play a crucial role in the progression of neuroinflammation following traumatic brain injury (TBI). Interleukin‐3 (IL‐3), a significant regulatory factor,
Nana Huang +18 more
wiley +1 more source
Co-existence in maize supply chains in Spain and Switzerland [PDF]
, 2007 The debate about co-existence usually focuses on the situation of neighbouring farms. Organic producers take the position that co-existence affects the whole supply chain.
Costa-Font, Montserrat +4 more
core
ELABELA Targets Mitochondria to Modulate Heart Development
Advanced Science, EarlyView.The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang +22 more
wiley +1 more source
Advanced Science, EarlyView.Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance +17 more
wiley +1 more source
EFSA Journal, 2017 Following the submission of application EFSA‐GMO‐RX‐005 under Regulation (EC) No 1829/2003 from Syngenta Crop Protection NV/SA, the Panel on Genetically Modified Organisms of the European Food Safety Authority (GMO Panel) was asked to deliver a ...
EFSA Panel on Genetically Modified Organisms (GMO) +20 more
doaj +1 more source
Attitudes and acceptance of South African urban consumers towards genetically modified white maize [PDF]
The introduction of genetically modified (GM) food products to food markets around the world, has led to considerable controversy. In many cases consumer attitudes and perceptions of GM food products were revealed as fears, concern for, and avoidance of ...
Doyer, Ockert T. +3 more
core +1 more source
Advanced Science, EarlyView.RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li +5 more
wiley +1 more source