Results 21 to 30 of about 8,837 (264)

Safety evaluation of the food enzyme aqualysin 1 from a genetically modified Bacillus subtilis (strain LMGS 25520)

EFSA Journal, 2018
The food enzyme considered in this opinion is aqualysin 1 (EC 3.4.21.111), produced from the genetically modified strain Bacillus subtilis LMGS 25520 by Puratos NV. The production strain was not detected in the food enzyme.
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF), Vittorio Silano, Claudia Bolognesi, Laurence Castle, Kevin Chipman, Jean‐Pierre Cravedi, Paul Fowler, Roland Franz, Konrad Grob, Rainer Gürtler, Trine Husøy, Sirpa Kärenlampi, Wim Mennes, Maria Rosaria Milana, Karla Pfaff, Gilles Riviere, Jannavi Srinivasan, Maria de Fátima Tavares Poças, Christina Tlustos, Detlef Wölfle, Holger Zorn, Andrew Chesson, Boet Glandorf, Lieve Herman, Klaus‐Dieter Jany, Francesca Marcon, André Penninks, Andrew Smith, Davor Želježić, Margarita Aguilera‐Gómez, Magdalena Andryszkiewicz, Davide Arcella, Natália Kovalkovičová, Yi Liu, Karl‐Heinz Engel   +34 more
doaj   +1 more source

Recent advances in recombinase polymerase amplification: Principle, advantages, disadvantages and applications

Frontiers in Cellular and Infection Microbiology, 2022
After the outbreak of SARS-CoV-2, nucleic acid testing quickly entered people’s lives. In addition to the polymerase chain reaction (PCR) which was commonly used in nucleic acid testing, isothermal amplification methods were also important nucleic acid ...
Meiying Tan, Chuan Liao, Lina Liang, Xueli Yi, Zihan Zhou, Guijiang Wei   +5 more
doaj   +1 more source

Safety evaluation of the food enzyme asparaginase from the genetically modified Aspergillus oryzae strain NZYM‐OA

EFSA Journal, 2023
The food enzyme asparaginase (l‐asparagine amidohydrolase; EC 3.5.1.1) is produced with the genetically modified microorganism Aspergillus oryzae strain NZYM‐OA by Novozymes A/S. The genetic modifications do not give rise to safety concerns.
EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), Claude Lambré, José Manuel Barat Baviera, Claudia Bolognesi, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Evgenia Lampi, Marcel Mengelers, Alicja Mortensen, Gilles Rivière, Inger‐Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Lieve Herman, Yrjö Roos, Jaime Aguilera, Magdalena Andryszkiewicz, Natalia Kovalkovicova, Yi Liu, Silvia Peluso, Giulio diPiazza, Rita Ferreira deSousa, Andrew Chesson   +26 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Safety management status for genetically modified microorganism and related products used for food industry

Zhongguo shipin weisheng zazhi
Genetically modified microorganism （GMM）， also known as recombinant DNA microorganism， means a micro-organism in which the genetic material has been altered in a way that does not occur naturally by mating and/or natural recombination.
HAN Xiaomin, BAI Li, LUO Xueyun, ZHANG Jiyue, SONG Yan, LIU Zhaoping, LI Ning   +6 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Safety of l‐lysine sulfate produced by fermentation with Escherichia coli CGMCC 3705 for all animal species

EFSA Journal, 2017
In 2015, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) issued an opinion on the safety and efficacy of l‐lysine sulfate produced by fermentation with Escherichia coli CGMCC 3705, when used as a nutritional additive ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Guido Rychen, Gabriele Aquilina, Giovanna Azimonti, Vasileios Bampidis, Maria de Lourdes Bastos, Georges Bories, Andrew Chesson, Pier Sandro Cocconcelli, Gerhard Flachowsky, Jürgen Gropp, Boris Kolar, Maryline Kouba, Marta López‐Alonso, Secundino López Puente, Alberto Mantovani, Baltasar Mayo, Fernando Ramos, Maria Saarela, Roberto Edoardo Villa, Pieter Wester, Lucio Costa, Noël Dierick, Lubomir Leng, Robert John Wallace   +24 more
doaj   +1 more source

Dual‐Layer Conducting and Redox Polymer Bioanodes for Synergistic Enhancement of Microbial Extracellular Electron Transfer

Advanced Functional Materials, EarlyView.
A hybrid PEDOT/Fc‐LPEI conducting/redox polymer bioanode synergistically improves microbial extracellular electron transfer (EET) in Shewanella oneidensis MR‐1. The dual‐layer interface delivers 18‐fold higher current output and 27‐fold greater charge collected than bare carbon felt, highlighting an effective strategy for high‐performance ...
Shenghan Gu, Saman Azhari, Kuniaki Nagamine, Takeo Miyake, Gábor Méhes   +4 more
wiley   +1 more source

Risks associated with the application of genetically modified microorganisms in terrestrial ecosystems [PDF]

FEMS Microbiology Letters, 1992
The application of genetically modified microorganisms (GEMMOs) in agriculture has great possibilities. However, the lack of knowledge on the occurrence of unwanted effects on the soil ecosystem still prevents the large-scale use of GEMMOs. Moreover, experimental work in risk assessment does not always fit the guidelines presented by regulatory ...
Smit, E., van Elsas, J.D., van Veen, J.A.   +2 more
openaire   +1 more source

Extrusion Bioprinting for Wound Healing: Innovations in Functionalized Bioinks and Bioprinting Technology

Advanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le, Anh Tuan Trong Tran, Ammara Waheed, Tran Thanh Tung, Dusan Losic   +4 more
wiley   +1 more source