Results 311 to 320 of about 505,318 (323)

Noonan syndrome: lessons learned from genetically modified mouse models

Expert Review of Endocrinology & Metabolism, 2017
Noonan syndrome is a RASopathy that results from activating mutations in different members of the RAS/MAPK signaling pathway. At least eleven members of this pathway have been found mutated, PTPN11 being the most frequently mutated gene affecting about 50% of the patients, followed by SOS1 (10%), RAF1 (10%) and KRAS (5%). Recently, even more infrequent
Alberto J. Schuhmacher, Isabel Hernández-Porras, Raquel García-Medina, Carmen Guerra   +3 more
openaire   +2 more sources

Genetically modified mouse as an experimental model in biomedicine

2001
no ...
openaire   +2 more sources

Using standard nomenclature to adequately name transgenes, knockout gene alleles and any mutation associated to a genetically modified mouse strain

Transgenic research, 2011
L. Montoliu, C. Bruce A. Whitelaw
semanticscholar   +1 more source

Sex hormones and their receptors in bone homeostasis: insights from genetically modified mouse models

Osteoporosis International, 2010
L. Vico, J. Vanacker
semanticscholar   +1 more source

Genetically Modified Mouse Models

, 2012
N. Balthasar
semanticscholar   +1 more source

Genetically Modified NAT Mouse Models

2018
Kim S. Sugamori, Denis M. Grant
openaire   +1 more source

Histological investigation in the brain of genetically modified mouse of schizophrenia

Neuroscience Research, 2011
Norio Ozaki, Keisuke Kuroda, Chikako Habuchi, Shuji Iritani, Hirotaka Sekiguchi, Yohta Torii, Kozo Kaibuchi   +6 more
openaire   +2 more sources

Unmasking different mechanical and energetic roles for the small heat shock proteins CryAB and HSPB2 using genetically modified mouse hearts

The FASEB Journal, 2008
I. Pinz, J. Robbins, N. Rajasekaran, I. Benjamin, J. Ingwall   +4 more
semanticscholar   +1 more source

Significant correction of pathology in brains of twitcher mice following injection of genetically modified mouse neural progenitor cells.

Molecular Genetics and Metabolism, 2009
M. Strazza, A. Luddi, M. Carbone, M. Rafi, E. Costantino‐Ceccarini, D. Wenger   +5 more
semanticscholar   +1 more source

EPR quantification of vascular nitric oxide production in genetically modified mouse models.

Nitric oxide, 2004
J. Khoo, N. Alp, J. Bendall, S. Kawashima, M. Yokoyama, Yinhua Zhang, B. Casadei, K. Channon   +7 more
semanticscholar   +1 more source