Results 41 to 50 of about 140,553 (337)

Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification

open access: yesFEBS Open Bio, EarlyView.
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski   +13 more
wiley   +1 more source

Introduction of the rd29A: AtDREB2A CA gene into soybean (Glycine max L. Merril) and its molecular characterization in leaves and roots during dehydration

open access: yesGenetics and Molecular Biology, 2013
The loss of soybean yield to Brazilian producers because of a water deficit in the 2011-2012 season was 12.9%. To reduce such losses, molecular biology techniques, including plant transformation, can be used to insert genes of interest into conventional ...
Cibelle Engels   +9 more
doaj   +1 more source

Implications of the EFSA Scientific Opinion on Site Directed Nucleases 1 and 2 for Risk Assessment of Genome-Edited Plants in the EU

open access: yesAgronomy, 2021
Genome editing is a set of techniques for introducing targeted changes in genomes. It may be achieved by enzymes collectively called site-directed nucleases (SDN).
Nils Rostoks
doaj   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

open access: yesFEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić   +3 more
wiley   +1 more source

Tanaman Genetically Modified Organism (GMO) dan Perspektif Hukumnya di Indonesia

open access: yesAl-Kauniyah Jurnal Biologi, 2017
Abstrak Genetically modified organism (GMO) merupakan organisme yang gen-gennya telah diubah dengan menggunakan teknik rekayasa genetika. Produk rekayasa genetika diklasifikasikan menjadi 4 macam, yaitu generasi pertama: satu sifat; generasi kedua ...
Yuwono Prianto, Swara Yudhasasmita
doaj   +1 more source

Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3

open access: yesFEBS Open Bio, EarlyView.
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno   +12 more
wiley   +1 more source

EUROPEAN INSTITUTIONAL FRAMEWORK FOR GENETICALLY MODIFIED ORGANISMS [PDF]

open access: yesInternational Journal Vallis Aurea, 2016
The aim of this paper is to present the composition and functioning of the EU institutions involved in receiving, analysing, approval or rejection of the application for the use of genetically modified organisms. The manner of participation of each institution is presented by using the comparative and historical method, as well as the method of ...
Antun Marinac, Mirela Mezak Matijević
openaire   +4 more sources

Hyperoxia Induced Alteration of Chromatin Structure in Human Bone Marrow Derived Primary Mesenchymal Stromal Cells

open access: yesAdvanced Biology, EarlyView.
Chromatin, which organizes DNA, changes its structure to adapt to stress like high oxygen levels (hyperoxia), which can damage cells. Researchers developed a technique to observe these changes and found variability in how different parts of chromatin remodel.
Lauren Monroe   +4 more
wiley   +1 more source

Mulberry leaf aqueous extract ameliorates blood glucose and enhances energy expenditure in obese C57BL/6J mice

open access: yesJournal of Functional Foods, 2019
Mulberry leaf garners much attention from researchers because of its hypoglycemic effect. This study’s objective was to determine the impact of mulberry leaf aqueous extract (MLAE) on decreasing blood glucose and promoting energy expenditure in obese ...
Xiaoyun He   +9 more
doaj  

The Regulation and Protection of Genetically Modified Food

open access: yesSociological Jurisprudence Journal, 2020
Genetically Modified foods are now being widely consumed. In 2011, more than 90% of corns and soybeans in the US are genetically modified. Research shows in America the people suffering from allergies are increasing.
Yuwono Prianto   +2 more
doaj  

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