Molecular Oncology, EarlyView.Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef +10 more
wiley +1 more source
Hybridization between transgenic and wild plants: environmental risk
Revista Colombiana de Biotecnología, 2011 Genetically modified products are widely commercialized in agricultural production. These include resistant plants to diseases, insects or herbicides, plants with capacity for longer storing times or better nutritional quality.
Alejandro Chaparro Giraldo
doaj
A conceptual framework for the design of environmental post-market monitoring of genetically modified plants [PDF]
, 2005 Olivier Sanvido +3 more
openalex +1 more source
Molecular Oncology, EarlyView.Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo +11 more
wiley +1 more source
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
Tropical Fruit Virus Resistance in the Era of Next-Generation Plant Breeding
SynBioPlant viral diseases constitute a major contributor to agricultural production losses, significantly impacting the economies of exporting countries by more than USD 30 billion annually. Understanding and researching the biology and genomics of viruses is
Marcella Silva Vieira +6 more
doaj +1 more source
Genetically modified plants are an alternative to oily fish for providing <i>n</i>-3 polyunsaturated fatty acids in the human diet: A summary of the findings of a Biotechnology and Biological Sciences Research Council funded project. [PDF]
Nutr Bull, 2021 West AL +5 more
europepmc +1 more source
A tiered system for assessing the risk of genetically modified plants to non-target organisms [PDF]
, 2006 Monica Garcia‐Alonso +10 more
openalex +1 more source
Effects on Capsicum annuum Plants Colonized with Trichoderma atroviride P. Karst Strains Genetically Modified in Taswo1, a Gene Coding for a Protein with Expansin-like Activity [PDF]
, 2021 Ricardo Sánchez-Cruz +13 more
openalex +1 more source
Molecular Oncology, EarlyView.This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source