Results 111 to 120 of about 3,336,192 (297)
Quasi-option values for enhanced information regarding genetically modified foods [PDF]
Issues concerning the long-term environmental and health risks associated with the production of genetically modified foods remain highly topical in Australia.
Bennett, Jeffrey W. +2 more
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Фактори експериментальної еволюції організмів, 2014 Aims. One of the main issues in plant biotechnology is the development of marker-free genetically modified species that increase the consumer acceptance. One of the molecular tools that can help to resolve is site-specific recombination.
А. С. Секан +2 more
doaj
Discussion - ecological challenges concerning the use of genetically modified moquitoes for disease control: synthesis and future perspectives [PDF]
, 2002 Discussion on the ecological aspects for the application of genetically modified mosquitoes for disease ...
Knols, B.G.J., Scott, T.W.
core
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
, 2011 This opinion provides guidance in the area of comparators taking into account the requirements for the molecular characterisation, the food and feed and the environmental risk assessments.
EFSA Panel on Genetically Modified Organisms (GMO)
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Acta Scientiarum Polonorum: Hortorum Cultus, 2013 Green biotechnology plays an important role in the modern agriculture. Recent progress in molecular biology and genetic engineering provides an opportunity of obtaining transgenic plants with improved characteristics, such as yield parameters ...
Magda Zapalska, Krzysztof Kowalczyk
doaj
CONSUMER ACCEPTANCE OF FOOD BIOTECHNOLOGY: WILLINGNESS TO BUY GENETICALLY MODIFIED FOOD PRODUCTS [PDF]
Biotechnology is often viewed as the defining technology for the future of food and agriculture with the potential to deliver a wide range of economic and health benefits.
Onyango, Benjamin M. +4 more
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