Results 91 to 100 of about 169,763 (304)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Guidance on the agronomic and phenotypic characterisation of genetically modified plants
EFSA Journal, 2015 This document provides guidance for the agronomic and phenotypic characterisation of genetically modified (GM) plants and clarifies the EFSA GMO Panel's view on how agronomic and phenotypic data support the risk assessment of GM plants.
EFSA Panel on Genetically Modified Organisms (GMO)
doaj +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Translocation of Insecticidal Bt Protein in Transgrafted Plants
BioTechTransgrafting constitutes a technique involving the integration of genetically modified (GM) and non-GM plant organisms. Typically, edible components derived from non-GM scions are categorized as non-GM food products, attributed to the absence of ...
Arisa Ando +8 more
doaj +1 more source
Who Owns Biological Diversity? A Brief Description of the Debate over the Rights to Biological Diversity in the North-South Context [PDF]
, 2000 For a long time, the genetic resources and biological diversity of all types of living organisms on the Earth were considered the common heritage of all of humanity.
Baier, Alexandra, Tappeser, Beatrix
core
Biotechnology, environmental forcing, and unintended trophic cascades [PDF]
, 2009 A long ongoing discussion between scientists and policy decision-makers seems to have entered recently into a new phase. The consequences of release of transgenic crops into the environment are being discussed not only by scientists but also by farmers ...
Lotz, L.A.P., Mulder, C.
core +2 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
U.S. EPA oversight of pesticide traits in genetically modified plants and recent biotechnology innovation efforts. [PDF]
Front Plant Sci, 2023 Mendelsohn M, Pierce AA, Striegel W.
europepmc +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Animal dietary exposure in the risk assessment of feed derived from genetically modified plants. [PDF]
EFSA J, 2023 EFSA Panel on Genetically Modified Organisms (GMO) +18 more
europepmc +1 more source