Results 61 to 70 of about 3,336,192 (297)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Data acquisition by farm questionnaires and linkage to other sources of data
, 2006 Monitoring is a statutory requirement for the cultivation of genetically modified (GM) crops in the EC. Questionnaires for farmers to report observations of effects potentially linked with the cultivation of GM crops can form a useful part of a ...
Beißner, L. +4 more
core +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Annals of Agricultural and Environmental Medicine, 2017 Introduction Agriculture based on genetically modified organisms plays an increasingly important role in feeding the world population, which is evidenced by a considerable growth in the size of land under genetically modified crops (GM).
Stanisław Lachowski +5 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Methodology and tools for data acquisition and statistical analysis
, 2006 Monitoring is a statutory requirement for the cultivation of genetically modified (GM) crops in the EU. To observe effects linked with the cultivation of GM crops data can be collected from different sources like farm questionnaires or existing ...
Beißner, L. +3 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Фактори експериментальної еволюції організмів, 2016 Aim. Development of a specialized database as a tool for optimization and cost reduction of GM detection analysis in seeds, food and feed. Methods. The project is implemented as online application based on Grails – high-performance software framework ...
С. І. Співак +6 more
doaj
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Introducing Genetically Modified Plants: Now or Later - An Option Value Approach [PDF]
Using market data, we have estimated the quasi option value of delaying to grow genetically modified corn and soybeans in Europe. We find that the current quasi option value of growing genetically modified soybeans and corn in Europe is high.
Brimi, Live +2 more
core