Results 31 to 40 of about 291,455 (281)

cual-id: Globally Unique, Correctable, and Human-Friendly Sample Identifiers for Comparative Omics Studies

mSystems, 2016
The number of samples in high-throughput comparative “omics” studies is increasing rapidly due to declining experimental costs. To keep sample data and metadata manageable and to ensure the integrity of scientific results as the scale of these projects ...
John H. Chase, Evan Bolyen, Jai Ram Rideout, J. Gregory Caporaso   +3 more
doaj   +1 more source

Patterns of Oral Microbiota Diversity in Adults and Children: A Crowdsourced Population Study. [PDF]

, 2020
Oral microbiome dysbiosis has been associated with various local and systemic human diseases such as dental caries, periodontal disease, obesity, and cardiovascular disease.
Burcham, Zachary M, Comstock, Sarah S, Garneau, Nicole L, Genetics of Taste Lab Citizen Scientists, Knight, Rob, Metcalf, Jessica L, Tucker, Robin M   +6 more
core  

Meeting report:Fungal genomics meets social media: Highlights of the 28th fungal genetics conference at asilomar [PDF]

, 2015
International ...
Alexander, William G., Barker, Bridget M., Di Pietro, Antonio, Harb, Omar S., Kamoun, Sophien, Martin, Francis, Momany, Michelle, Pires, J. Chris, Stajich, Jason E., Thomma, Bart P H J, Unruh, Sarah   +10 more
core   +3 more sources

Enabling precision medicine in neonatology, an integrated repository for preterm birth research. [PDF]

, 2018
Preterm birth, or the delivery of an infant prior to 37 weeks of gestation, is a significant cause of infant morbidity and mortality. In the last decade, the advent and continued development of molecular profiling technologies has enabled researchers to ...
Anderson, Rebecca, Banerjee, Payal, Butte, Atul J, Chappell, Joanne, Chubiz, Jessica, England, Sarah K, Grobman, William, Kim, Mara, Leite, Rita, Liu, Rebecca, March of Dimes Prematurity Research Centers, Parry, Samuel, Quaintance, Cecele C, Rokas, Antonis, Shaw, Gary M, Simpson, Joe Leigh, Sirota, Marina, Thomas, Cristel G, Thomson, Elizabeth, Wong, Ronald J, Zhang, Ge, Zuhl, Maya   +21 more
core   +4 more sources

Adaptive tuning of mutation rates allows fast response to lethal stress in Escherichia coli

eLife, 2017
While specific mutations allow organisms to adapt to stressful environments, most changes in an organism's DNA negatively impact fitness. The mutation rate is therefore strictly regulated and often considered a slowly-evolving parameter.
Toon Swings, Bram Van den Bergh, Sander Wuyts, Eline Oeyen, Karin Voordeckers, Kevin J Verstrepen, Maarten Fauvart, Natalie Verstraeten, Jan Michiels   +8 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Antibacterial Activity of Metabolites of Endophytic Bacillus subtilis Isolated From Selected Ethiopian Medicinal Plants

International Journal of Microbiology
Antimicrobial resistance remains a global concern, and there has been sustained exploration of natural products with therapeutic effects. Endophytes are among the potential microorganisms considered as the treasure chest for bioactive secondary ...
Tsedale Tasew, Dagim Jirata Birri, Fitsum Tigu, Dereje Beyene, Tegenu Gelana, Ketema Tolossa, Balako Gumi, Tigist Getachew, Iris Bertani, Vittorio Venturi, Dejene Guta, Asnake Desalegn   +11 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Biotechnological Potential of Lactic Acid Bacteria Isolated From Ethiopian Honey Wine, Tej

International Journal of Microbiology
Some members of the lactic acid bacteria (LAB) have been used as probiotics. Ethiopian honey wine, Tej, may be a useful source of potential probiotic bacteria.
Minyilal Sisay, Asnake Desalegn, Fitsum Tigu, Mogessie Ashenafi, Feng-Yan Bai, Dagim Jirata Birri   +5 more
doaj   +1 more source

The Dynamic Transition of Persistence toward the Viable but Nonculturable State during Stationary Phase Is Driven by Protein Aggregation

mBio, 2021
Decades of research into bacterial persistence has been unable to fully characterize this antibiotic-tolerant phenotype, thereby hampering the development of therapies effective against chronic infections.
Liselot Dewachter, Celien Bollen, Dorien Wilmaerts, Elen Louwagie, Pauline Herpels, Paul Matthay, Ladan Khodaparast, Laleh Khodaparast, Frederic Rousseau, Joost Schymkowitz, Jan Michiels   +10 more
doaj   +1 more source