Results 31 to 40 of about 282,122 (210)

Variable responses of human and non-human primate gut microbiomes to a Western diet [PDF]

open access: yes, 2015
BACKGROUND: The human gut microbiota interacts closely with human diet and physiology. To better understand the mechanisms behind this relationship, gut microbiome research relies on complementing human studies with manipulations of animal models ...
Amato, Katherine R.   +13 more
core   +5 more sources

Enhancement of feather degrading keratinase of Streptomyces swerraensis KN23, applying mutagenesis and statistical optimization to improve keratinase activity

open access: yesBMC Microbiology, 2023
In this study, 25 actinomyces isolates were obtained from 10 different poultry farms and tested for their keratinase activity. The isolate with the highest keratinase activity was identified through molecular identification by PCR and sequencing of the ...
Nagwa M. Abd El-Aziz   +2 more
doaj   +1 more source

cual-id: Globally Unique, Correctable, and Human-Friendly Sample Identifiers for Comparative Omics Studies

open access: yesmSystems, 2016
The number of samples in high-throughput comparative “omics” studies is increasing rapidly due to declining experimental costs. To keep sample data and metadata manageable and to ensure the integrity of scientific results as the scale of these projects ...
John H. Chase   +3 more
doaj   +1 more source

Advancing the Microbiome Research Community [PDF]

open access: yes, 2014
The human microbiome has become a recognized factor in promoting and maintaining health. We outline opportunities in interdisciplinary research, analytical rigor, standardization, and policy development for this relatively new and rapidly developing ...
Brown, C. Titus   +14 more
core   +2 more sources

Advancing Drug Resistance Research Through Quantitative Modeling and Synthetic Biology [PDF]

open access: yesFrontiers in Bioengineering and Biotechnology, 8: 583415 (2020), 2020
Antimicrobial resistance is an emerging global health crisis that is undermining advances in modern medicine and, if unmitigated, threatens to kill 10 million people per year worldwide by 2050. Research over the last decade has demonstrated that the differences between genetically identical cells in the same environment can lead to drug resistance ...
arxiv   +1 more source

Adaptive tuning of mutation rates allows fast response to lethal stress in Escherichia coli

open access: yeseLife, 2017
While specific mutations allow organisms to adapt to stressful environments, most changes in an organism's DNA negatively impact fitness. The mutation rate is therefore strictly regulated and often considered a slowly-evolving parameter.
Toon Swings   +8 more
doaj   +1 more source

Individual and collective identification in contemporary forensics [PDF]

open access: yes, 2020
It has long been understood that individual and collective identification are inexorably intertwined. This convergence is not limited to genetics. This paper discusses the convergence of individual and collective identification in a comparative analysis ...
Cole, SA
core  

Global divergence of microbial genome sequences mediated by propagating fronts [PDF]

open access: yes, 2005
We model the competition between recombination and point mutation in microbial genomes, and present evidence for two distinct phases, one uniform, the other genetically diverse. Depending on the specifics of homologous recombination, we find that global sequence divergence can be mediated by fronts propagating along the genome, whose characteristic ...
arxiv   +1 more source

Relationship between fitness and heterogeneity in exponentially growing microbial populations [PDF]

open access: yes, 2021
Despite major environmental and genetic differences, microbial metabolic networks are known to generate consistent physiological outcomes across vastly different organisms. This remarkable robustness suggests that, at least in bacteria, metabolic activity may be guided by universal principles.
arxiv   +1 more source

Fecal microbiota transplants: Emerging social representations in the English-language print media [PDF]

open access: yes, 2019
open access articleThis study investigates how English-language news sources have represented fecal microbiota transplants (FMT). FMT involves transferring stool from a healthy donor to a recipient with a dysfunctional intestinal flora in order to ...
Jaspal, Rusi   +2 more
core   +4 more sources

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