Results 231 to 240 of about 167,852,344 (298)

Complementing Engel Classification: Postoperative Scalp EEG as an Objective Indicator in SEEG‐Guided Radiofrequency Thermocoagulation—A Seizure‐Onset Pattern‐Based Stratified Analysis—

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) is a minimally invasive therapy for drug‐resistant focal epilepsy. However, the relationship between specific seizure‐onset patterns (SOPs), particularly low‐voltage fast activity (LVFA), and postoperative scalp EEG normalization remains inadequately ...
Yi‐qing Yang, Rui Zhang, Haiyan Ma, Lu Yang, Xuefeng Qu, Qiqi Chen, Yan Zhang   +6 more
wiley   +1 more source

Sex differences in transcription-associated mutagenesis in the human germline. [PDF]

Genetics
Wyman MJ, Agarwal I, de Manuel M, Spisak N, Przeworski M.   +4 more
europepmc   +1 more source

Stage‐Specific Patterns of Imaging and Non‐Motor Biomarkers in Spinocerebellar Ataxia Type 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Advancements in disease‐modifying therapies for spinocerebellar ataxia Type 3 (SCA3) underscore the need for robust biomarkers to monitor disease progression and evaluate treatment efficacy. Although motor phenotypes have been well characterized, less is known about non‐motor and imaging‐based features across different disease stages.
Chun Li, Zhi‐Xian Ye, Xuan‐Yu Chen, Liang‐Liang Qiu, Zhi‐li Chen, Yu‐Sen Qiu, Wei Lin, Ru‐Ying Yuan, Xin‐Tong Yu, Chun‐Yu Huang, Xin‐Yuan Chen, Min‐Ting Lin, Jian‐Ping Hu, Wan‐Jin Chen, Ning Wang, Shao‐Bo Yao, Shi‐Rui Gan, Ying Fu   +17 more
wiley   +1 more source

A nationwide prospective randomized trial for diagnosing developmental disorders demonstrates genome sequencing outperforms standard of care. [PDF]

Genome Med
Geysens M, Souche E, Baroni MC, Benoit V, Beyltjens T, Bossuyt W, Bours V, Crabbé M, Croes D, De Smet M, Désir J, Devriendt K, Dheedene A, Dimitrov BI, Janssens K, Kumps C, Lumaka A, Menten B, Meuwissen M, Monestier O, Mortier G, Olsen C, Palmeira L, Peeters H, Pölsler L, Revencu N, Roland D, Soblet J, Sznajer Y, Taziaux S, Van Esch H, Vandeweyer G, Vantroys E, Vilain C, Wiame E, Van Den Bogaert K, Vermeesch JR.   +36 more
europepmc   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source

Neuronal Nrf/SKN-1B controls a sexually dimorphic neuroendocrine pathway for C. elegans exploratory behaviour. [PDF]

PLoS Genet
McLean N, Gami MS, Dennis N, Malik Y, De Araujo J, Evans J, Bennett L, Ezcurra M, Tullet JMA.   +8 more
europepmc   +1 more source

A systematic review and critical analysis of the evidence for transmission ratio distortion in humans. [PDF]

Genetics
Dai Z, Costain G.
europepmc   +1 more source

Knowledge, Attitudes, and Perceived Barriers to Genetics and Precision Medicine Among Rural Participants in a Large Academic Biobank: A Mixed-Methods Study. [PDF]

J Pers Med
MacNeal M, Bihlmeyer NA, Haga SB.
europepmc   +1 more source

Genetic influences on accelerometer-measured physical activity and sedentary time in children: sex-specific patterns from a Swedish twin study. [PDF]

Sci Rep
Helgadóttir B, Wang R, Kuja-Halkola R, Wiklund CA, Ekblom Ö, Ekblom MM.   +5 more
europepmc   +1 more source