Results 251 to 260 of about 167,852,344 (298)
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Journal of Mental Science, 1962
It is more than twenty years since Lang advanced the hypothesis that some male homosexuals are sex intergrades with male morphological sex characteristics but a female chromosomal pattern (Lang, 1940). Is there now sufficient evidence to prove or disprove the theory?
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It is more than twenty years since Lang advanced the hypothesis that some male homosexuals are sex intergrades with male morphological sex characteristics but a female chromosomal pattern (Lang, 1940). Is there now sufficient evidence to prove or disprove the theory?
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Genetic mechanisms of sex differentiation
Current Opinion in Pediatrics, 1996Cloning of the SRY sex-determining locus on the Y chromosome has stimulated research on the genetic mechanisms of sex determination. It now appears that SRY is not the only gene required for testicular differentiation; X-linked and autosomal genes are also important.
N, Josso, R, Rey
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Genetics of Sex Differences in Immunity
2023Women have a stronger immune response and a higher frequency of most autoimmune diseases than men. While much of the difference between men and women is due to the effect of gonadal hormones, genetic differences play a major role in the difference between the immune response and disease frequencies in women and men.
Shani T, Gal-Oz, Tal, Shay
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The roles of sex and genetics in the MPN
2022The Philadelphia chromosome negative myeloproliferative neoplasms(MPNs), polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF) are acquired hematopoietic stem cell disorders driven by activating mutations of intracellular signal transduction pathways that control the production of circulating blood cells.
Alison R, Moliterno, Evan M, Braunstein
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Presse medicale (Paris, France : 1983), 1992
The sex gene SRY has recently been characterized after years of research during which the candidate genes HY and ZFY were excluded. SRY does have all the characteristics expected of the sex gene: it is located on chromosome Y of all mammals, including man; it is specifically expressed in male gonads during early embryonic development mutations and ...
E, Vilain +3 more
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The sex gene SRY has recently been characterized after years of research during which the candidate genes HY and ZFY were excluded. SRY does have all the characteristics expected of the sex gene: it is located on chromosome Y of all mammals, including man; it is specifically expressed in male gonads during early embryonic development mutations and ...
E, Vilain +3 more
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The Molecular Genetics of Sex Determination and Sex Reversal in Mammals
Seminars in Reproductive Medicine, 2012The process of sex determination in mammals normally unfolds in three distinct stages: (1) establishment of chromosomal sex at fertilization (XX or XY); (2) commitment to the appropriate pathway of gonadal differentiation with respect to chromosomal sex, through the action (or absence) of the Y chromosome gene SRY; and (3) correct development of ...
Peter Koopman, Alexander Quinn
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Genetic Sex Identification in Orangutans
Anthropologischer Anzeiger, 2003To date, no established protocol for genetic sex identification in orangutans (Pongo pygmaeus) exists. In nearly all apes (gibbons, gorillas, chimpanzees, and humans), genetic sex identification is possible using the amelogenin gene because copies located on X and Y chromosomes have different sizes.
Michael E, Steiper, Maryellen, Ruvolo
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Genetic Error, Sex, and Diploidy
Journal of Heredity, 1993Mathematical models and experiments on transformation are reported testing the hypothesis that sex and diploidy evolved as a DNA repair system. The models focus on the origin of diploidy and sex by studying selection between asexual haploids, sexual haploids, and diploids.
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Casopis lekaru ceskych, 1993
A stepwise resolution of the role of individual genes known to play role in sex determination is presented. Cytogenetic abnormalities e.g. male phenotype with XX and female phenotype with XY gonosomal complements helped substantially to ascertain SRY (Sex region of Y) gene activity to be essential for sex phenotype development control.
E, Payen, M, Fellous
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A stepwise resolution of the role of individual genes known to play role in sex determination is presented. Cytogenetic abnormalities e.g. male phenotype with XX and female phenotype with XY gonosomal complements helped substantially to ascertain SRY (Sex region of Y) gene activity to be essential for sex phenotype development control.
E, Payen, M, Fellous
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Journal of Endocrinology, 1995
Introduction In mammals, sex is determined by the presence or absence of the Y chromosome. The first event in sexual differentiation is the differentiation of the bipotential gonad into testes or ovaries. All subsequent sexual differentiation is under hormonal control of the testes or ovaries. The genetic entity
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Introduction In mammals, sex is determined by the presence or absence of the Y chromosome. The first event in sexual differentiation is the differentiation of the bipotential gonad into testes or ovaries. All subsequent sexual differentiation is under hormonal control of the testes or ovaries. The genetic entity
openaire +2 more sources