Results 61 to 70 of about 8,074 (289)

Use of CRISPR/Cas9-Based Gene Editing to Simultaneously Mutate Multiple Homologous Genes Required for Pollen Development and Male Fertility in Maize

Cells, 2022
Male sterility represents an important trait for hybrid breeding and seed production in crops. Although the genes required for male fertility have been widely studied and characterized in many plant species, most of them are single genic male-sterility ...
Xinze Liu, Shaowei Zhang, Yilin Jiang, Tingwei Yan, Chaowei Fang, Quancan Hou, Suowei Wu, Ke Xie, Xueli An, Xiangyuan Wan   +9 more
doaj   +1 more source

Differential gene expression in an elite hybrid rice cultivar (Oryza sativa, L) and its parental lines based on SAGE data [PDF]

, 2007
Background It was proposed that differentially-expressed genes, aside from genetic variations affecting protein processing and functioning, between hybrid and its parents provide essential candidates for studying heterosis or hybrid vigor.
Shuhui Song, Hongzhu Qu, Chen Chen, Songnian Hu, Jun Yu   +4 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Genetic characterisation of a novel male sterile two-type line system 19F08AB in Brassica napus L.

Czech Journal of Genetics and Plant Breeding
Rapeseed (Brassica napus L.) is a major global oilseed crop and exhibits significant heterosis. The discovery and characterisation of novel male-sterile accessions remain fundamental for harnessing heterosis in rapeseed breeding. Previously, we developed
Lirong Zhao, Zikang Chen, Ruting Xie, Hui Dong, Haibo Yu, Dongsuo Zhang, Zhaoxin Hu, Shengwu Hu   +7 more
doaj   +1 more source

International genetic, cytogenetic and germplasm resources for cotton genomics and genetic improvement [PDF]

, 2008
A general understanding of the nature, uses and need of cotton germplasm collections is important to maintaining support for them and their utilization. Such support is vital to addressing the future challenges and needs of cotton, which will be many and
Abdurakhmonov, Ibrokhim, Dessauw, Dominique, Frelichowski, James, Kohel, Russell J., Lacape, Jean-Marc, Mergeai, Guy, Saha, Sukumar, Sanamyan, Marina, Stelly, David M., Wang, Kunbo, Zhang Tianzheng,, Zhou, Baoliang   +11 more
core  

Current advances in genomics and breeding of leaf chicory (Cichorium intybus L.) [PDF]

, 2016
This review gives an overview of agricultural topics on a non-model species, in other words, leaf chicory. Often classified as a minor crop, \u201cRadicchio\u201d, the Italian name of leaf chicory, is assuming a very important role at both a local and ...
Barcaccia, Gianni, Ghedina, Andrea, Lucchin, Margherita   +2 more
core   +2 more sources

Field evaluation of thermosensitive genic male sterile lines

, 1998
This article 'Field evaluation of thermosensitive genic male sterile lines' appeared in the International Rice Research Notes series, created by the International Rice Research Institute (IRRI) to expedite communication among scientists concerned with the development of improved technology for rice and rice-based systems.
Vijakumar, C. H. M., Ahmed, M., Viraktamath, B. C., Ramesha, M. S., Singh, S.   +4 more
openaire   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Genetic inheritance and identification of molecular markers linked tomale sterility in African marigold (Tagetes erecta L.)

Journal of Horticultural Sciences
The demand for hybrid varieties of African marigold (Tagetes erecta L.) is on the rise due to the increased productivity and uniformity exhibited by F1 hybrids.
Sumalatha Akkalareddy, D C Lakshmana Reddy, M Arivalagan, V V Bhaskar, Tejaswini Prakash   +4 more
doaj   +1 more source