Results 101 to 110 of about 66,736 (236)

Applications of bioactive herbal extracts in dressing materials for skin wound repair: Ingredients, mechanisms and innovations

open access: yesInterdisciplinary Medicine, EarlyView.
Abstract The skin, as the body's largest organ, plays essential roles in protection, immune regulation, and homeostasis. Skin trauma, especially chronic wounds such as diabetic ulcers, poses significant clinical challenges. Traditional treatments, while often effective, can be costly and pose risks.
Boxiang Yang   +12 more
wiley   +1 more source

Genistein induces apoptosis of colon cancer cells by reversal of epithelial-to-mesenchymal via a Notch1/NF-κB/slug/E-cadherin pathway

open access: yesBMC Cancer, 2017
Genistein has been known to inhibit proliferation and induce apoptosis in several kinds of cancer cells. While knowledge of genistein in regulating epithelial mesenchymal transition (EMT) of colon cancer cells is unknown.
Panpan Zhou   +5 more
semanticscholar   +1 more source

Molecular docking‐guided in‐depth investigation of the biological activities and phytochemical and mineral profiles of endemic Phlomis capitata

open access: yesJournal of the Science of Food and Agriculture, Volume 105, Issue 7, Page 3760-3775, May 2025.
Abstract BACKGROUND Phlomis capitata is an endemic species of flowering aromatic and medicinal plant in the family Lamiaceae, native to regions of the Mediterranean and nearby areas. Understanding the chemical compounds present in P. capitata can reveal potential medicinal properties.
Ebubekir İzol
wiley   +1 more source

Isoliquiritigenin, a Strong nod Gene- and Glyceollin Resistance- Inducing Flavonoid from Soybean Root Exudate [PDF]

open access: yes, 1992
Isoflavonoid signal molecules from soybean (Glycine max (L.) Merr.) seed and root exudate induce the transcription of nodulation (nod) genes in Bradyrhizobium japonicum. In this study, a new compound with symbiotic activity was isolated from soybean root
Brandt, Sebastian   +3 more
core  

Correction of Huntington’s Disease Phenotype by Genistein-Induced Autophagy in the Cellular Model

open access: yesNeuromolecular medicine, 2018
Huntington’s disease (HD) is a monogenic disorder, caused by mutations in the HTT gene which result in expansion of CAG triplets. The product of the mutated gene is misfolded huntingtin protein that forms aggregates leading to impairment of neuronal ...
Karolina Pierzynowska   +6 more
semanticscholar   +1 more source

Inhalable Nano Formulation of Cabazitaxel: A Comparative Study with Intravenous Route

open access: yesMacromolecular Bioscience, Volume 25, Issue 5, May 2025.
Nano drug formulation shows no signs of toxicity for IV and INH routes, whereas higher systemic toxicity occurs in free drug formulation in both. Inhalable nano formulation provides higher and longer retention in deep lung regions due to its size and defies rapid systemic absorption in the lungs.
Elif Kaga   +3 more
wiley   +1 more source

Evaluación de fibra dietética, isoflavonas y compuestos fenólicos con propiedades antioxidantes y antimicrobianas de quinoa (Chenopodium quinoa Willd.) [PDF]

open access: yes, 2018
The consumption of quinoa (Chenopodium quinoa Willd.) has been steadily increasing due to its high nutritional value and health benefits associated with its high antioxidant capacity.
Agüero, Maria Victoria   +7 more
core  

Genistein-triggered anticancer activity against liver cancer cell line HepG2 involves ROS generation, mitochondrial apoptosis, G2/M cell cycle arrest and inhibition of cell migration

open access: yesArchives of medical science : AMS, 2018
Introduction Liver cancer is one of the most common malignancies across the globe and one of the major causes of cancer-related mortality. With limited available treatment options, there is an urgent need to look for new available options.
Qian Zhang, Juan Bao, Jiehua Yang
semanticscholar   +1 more source

Angiogenesis as a Therapeutic Target of (Poly)phenols: Tackling Cancer and Vascular‐Related Complications

open access: yesMolecular Nutrition &Food Research, EarlyView.
(Poly)phenols constitute a source of natural therapeutic molecules capable of targeting angiogenesis in different scenarios. This review summarizes the current evidence of the role of (poly)phenols in modulating angiogenesis. The reader can find a compilation of preclinical and human investigations describing pro‐ and anti‐angiogenic effects of these ...
María Ángeles Ávila‐Gálvez   +5 more
wiley   +1 more source

Neuroprotective effects of genistein on SH-SY5Y cells overexpressing A53T mutant α-synuclein

open access: yesNeural Regeneration Research, 2018
Genistein, a potent antioxidant compound, protects dopaminergic neurons in a mouse model of Parkinson's disease. However, the mechanism underlying this action remains unknown.
Huancheng Wu   +9 more
semanticscholar   +1 more source

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