Results 71 to 80 of about 8,062 (174)

Exploring of Antidepressant Components and Mechanisms of Zhizichi Decoction: Integration of Serum Pharmacochemistry, Network Pharmacology and Anti‐inflammatory Analysis Verification

open access: yesAnalytical Science Advances, Volume 6, Issue 1, June 2025.
ABSTRACT Using LC–MS to screen and analyse the characteristics of components and biological systems is a new approach to study the pharmacological substance basis of traditional Chinese medicine, which has strong novelty in analytical science. This study analyses the antidepressant material basis of Zhizichi decoction through the integration strategy ...
Chuan Chai   +7 more
wiley   +1 more source

Organic Functional Groups and Their Substitution Sites in Natural Flavonoids: A Review on Their Contributions to Antioxidant, Anti‐Inflammatory, and Analgesic Capabilities

open access: yesFood Science &Nutrition, Volume 13, Issue 5, May 2025.
Analgesic flavonoids exhibit both antioxidant and anti‐inflammatory properties, with prenylated groups potentially enhancing their effects. In contrast, biflavonoids generally demonstrate either anti‐inflammatory or analgesic capabilities. Furthermore, key substitution sites in these compounds can be fully replaced by various organic functional groups,
Jingxian An   +5 more
wiley   +1 more source

Genistein diet improves body weight, serum glucose and triglyceride levels in both male and female ob/ob mice

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2019
Schuyler Rockwood,1 Daniel Mason,1 Ryan Lord,1 Peter Lamar,2 Walter Prozialeck,2 Layla Al-Nakkash3 1Arizona College of Osteopathic Medicine, Midwestern University, Glendale, AZ, USA; 2Department of Pharmacology, College of Graduate Studies, Midwestern ...
Rockwood S   +5 more
doaj  

Thrombin‐induced human platelet aggregation is inhibited by protein‐tyrosine kinase inhibitors, ST638 and genistein [PDF]

open access: bronze, 1992
Momoyo Asahi   +7 more
openalex   +1 more source

Molecular docking‐guided in‐depth investigation of the biological activities and phytochemical and mineral profiles of endemic Phlomis capitata

open access: yesJournal of the Science of Food and Agriculture, Volume 105, Issue 7, Page 3760-3775, May 2025.
Abstract BACKGROUND Phlomis capitata is an endemic species of flowering aromatic and medicinal plant in the family Lamiaceae, native to regions of the Mediterranean and nearby areas. Understanding the chemical compounds present in P. capitata can reveal potential medicinal properties.
Ebubekir İzol
wiley   +1 more source

A highly selective cell-based fluorescent biosensor for genistein detection

open access: yesEngineering Microbiology, 2023
Genistein, an isoflavone found mainly in legumes, has been shown to have numerous health benefits for humans. Therefore, there is substantial interest in producing it using microbial cell factories.
Lucy Fang-I Chao   +2 more
doaj  

Natural products targeting tumour angiogenesis

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 10, Page 2094-2136, May 2025.
Abstract Tumour angiogenesis is the formation of new blood vessels to support the growth of a tumour. This process is critical for tumour progression and metastasis, making it an attractive approach to cancer therapy. Natural products derived from plants, animals or microorganisms exert anti‐angiogenic properties and can be used to inhibit tumour ...
Xiaohua Lu   +2 more
wiley   +1 more source

Effects of dose and route of administration of genistein on isoflavone concentrations in post-weaned and gestating sows

open access: yesAnimal, 2013
Phytoestrogens could be a useful tool in swine husbandry practices because of their structural and functional similarities to estradiol. The goal of this study was to compare various routes and doses of administration of the phytoestrogen genistein in ...
C. Farmer, P. Robertson, G.S. Gilani
doaj  

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