Results 81 to 90 of about 31,152 (194)
Inhibitory Effect of Genistein on α-Glucosidase and Its Molecular Mechanism
Shipin gongye ke-jiTo investigate the inhibitory effects of genistein on α-glucosidase activity, the effects of genistein on starch digestion characteristics were determined by in vitro digestion assays. The type and molecular mechanism of inhibition were examined based on
Jianhui JIA +5 more
doaj +1 more source
Die therapeutischen Effekte von Estradiol, Dihydrotestosteron, Genistein und Equol auf den osteoporotischen Knochen der orchidektomierten männlichen Sprague-Dawley-Ratte [PDF]
, 2010 Elena Vorwerk
openalex +1 more source
International Journal of Cancer, Volume 158, Issue 3, Page 475-487, 1 February 2026.Abstract Hepatocellular carcinoma (HCC) represents the predominant form of primary liver cancer and is frequently identified at a late stage, necessitating systemic therapy. However, resistance to first‐line tyrosine kinase inhibitor therapies, such as sorafenib and lenvatinib, remains a significant clinical challenge.
Longtao Zhao +6 more
wiley +1 more source
Molecular Mechanisms of Action of Genistein in Cancer: Recent Advances
Frontiers in Pharmacology, 2019 Background: Genistein is one among the several other known isoflavones that is found in different soybeans and soy products. The chemical name of genistein is 4′,5,7-trihydroxyisoflavone.
Hardeep Singh Tuli +9 more
doaj +1 more source
Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions
MedComm, Volume 7, Issue 2, February 2026.Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian +8 more
wiley +1 more source
Advanced Healthcare Materials, Volume 15, Issue 1, 9 January 2026.This review summarizes the main uptake pathways of bioactive glass nanoparticles (BGNs) and their intracellular localization, highlighting that BGNs are mainly internalized and entrapped within endosomes/lysosomes. Strategies for controlled intracellular ion release, with implications for targeted modulation of cell behavior, are discussed. The need to
Andrada‐Ioana Damian‐Buda +1 more
wiley +1 more source
Advanced Science, Volume 13, Issue 5, 27 January 2026.Extracellular vesicle (EV)‐packaged CDC37 are released from TMBhiCTLlo breast cancer cells with high CDC37 expression, and internalized into endo/phagosomes of dendritic cells (DCs). Within these compartments, CDC37 locked HSP90–antigen complex, preventing antigen release into the cytosol.
Ruxin Wang +10 more
wiley +1 more source
Biopolymers, Volume 117, Issue 1, January 2026.ABSTRACT The effect of the enzyme‐mediated poly(gallic acid) (PGAL) as a potential redox regulator or redox activity compound (RAC) on the morphology of human neuroblastoma SH‐SY5Y cells and its methionine synthase (MS) activities is contrasted to those for disrupting compounds (EDC).
Gabriela García‐Cerón +7 more
wiley +1 more source
Genistein treatment increases bone mass in obese, hyperglycemic mice
Diabetes, Metabolic Syndrome and Obesity, 2016 Richard M Michelin,1 Layla Al-Nakkash,2 Tom L Broderick,3 Jeffrey H Plochocki4 1Arizona College of Osteopathic Medicine, 2Department of Physiology, 3Laboratory of Diabetes and Exercise Metabolism, Department of Physiology, 4Department of Anatomy, Arizona
Michelin RM +3 more
doaj