Results 71 to 80 of about 9,204 (292)

Two nouns in partitives: evidence from Japanese

open access: yesGlossa, 2017
We consider the proposal that partitives always contain two positions for nouns which may be filled by silent material from the perspective of Japanese.
Kazuko Yatsushiro, Uli Sauerland
doaj   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Role of Verb Semantics in Genitive Alternations: Genitive of Negation and Genitive of Intensionality

open access: yes, 2020
The Role of Verb Semantics in Genitive Alternations: Genitive of Negation and Genitive of Intensionality [Электронный ресурс] / Barbara H. Partee, Vladimir Borschev, Elena Paducheva, Yakov Testelets, Igor Yanovich// OSLa : Oslo Studies in Language ...

core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Das deutsche Gespenst verflüchtigt sich allmählich

open access: yesAkademisk Kvarter, 2012
Jan T. Schlosser and Sandra Tyra Helms Das deutsche Gespenst verflüchtigt sich allmählich Die Darstellung Deutschlands in Weekendavisen. (The German ghost gradually escapes The depiction of Germany in Weekendavisen).
Jan T. Schlosser, Sandra Tyra Helms
doaj   +1 more source

Mutilación genital = Genital mutilation

open access: yesEUNOMÍA. Revista en Cultura de la Legalidad, 2017
Resumen: La mutilación genital constituye una realidad no erradicada que representa una grave vulneración de numerosos derechos fundamentales. Así, numerosos instrumentos internacionales y supranacionales se han ocupado de la misma y por ello ha sido tipificada penalmente en el ordenamiento jurídico español.
openaire   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Genitive of negation in Gothic

open access: yes, 2020
The “genitive of negation” (GenNeg) is a morphosyntactic phenomenon that has seldom been addressed in Germanic, and Gothic in particular. By means of internal and typological comparison, this article aims to pinpoint the major features of this phenomenon,
Bucci, Giacomo
core   +1 more source

Animacy in early New Zealand english [PDF]

open access: yes, 2012
The literature suggests that animacy effects in present-day spoken New Zealand English (NZE) differ from animacy effects in other varieties of English. We seek to determine if such differences have a history in earlier NZE writing or not.
Hundt, Marianne, Szmrecsanyi, Benedikt
core   +1 more source

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