Results 61 to 70 of about 1,199,260 (278)

Induced Dryness Stress on Human Vaginal Epithelium: The Efficacy of a New Vaginal Gel

open access: yesGels, 2021
An experimental model of dryness on vaginal mucosa is proposed to assess the efficacy of a new vaginal gel (Respecta® Hydragel Ref 17031). The dryness model was induced on reconstituted human vaginal epithelium (HVE) by incubating the tissues in modified
Guglielmo Stabile   +3 more
doaj   +1 more source

Heterozygous Variants in LRP1 Cause a Neurodevelopmental Disorder With Congenital Heart Defects

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT LRP1 encodes the low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1), a transmembrane protein involved in endocytosis and activation of multiple signaling pathways. LRP1 variants have been implicated in the pathogenesis of congenital heart defects (CHD), Alzheimer's disease, and neurodevelopmental disorders (NDD).
Alyssa L. Rippert   +31 more
wiley   +1 more source

Spectrum of Congenital Anomalies in Myhre Syndrome—Insights Into Effects Brought by Altered TGF‐β Signaling via Gain‐of‐Function Variants in SMAD4

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome is a rare genetic disorder characterized by progressive multisystem involvement. Gain‐of‐function missense heterozygous variants affecting the Ile500 residue and Arg496 residue of the SMAD4 gene are implicated in this condition.
Kawmadi Gunawardena   +13 more
wiley   +1 more source

ASSOCIATION OF DIABETES AND VAGINAL MICROBIOTA WITH THE GENITOURINARY SYNDROME OF MENOPAUSE

open access: yes, 2023
ASSOCIATION OF DIABETES AND VAGINAL MICROBIOTA WITH THE GENITOURINARY SYNDROME OF ...
Michelle Shardell (343323)   +6 more
core   +1 more source

Hormone therapy for genitourinary syndrome of menopause: reality and prospects

open access: yesКлинический разбор в общей медицине
Genitourinary syndrome of menopause still represents one of the most pressing unresolved issues of modern gynecology. High prevalence and the data suggesting a marked decline in the quality of life in general and sexual life in particular in patients of ...
Mekan R. Orazov   +2 more
doaj   +1 more source

Reframing the Gut–Brain Axis: The Gut Wall as a Neural Immune Interface in Multiple Sclerosis and Autoimmune Neurological Diseases

open access: yesAnnals of Neurology, EarlyView.
Gut wall physiology in multiple sclerosis (MS) and autoimmune neurologic diseases remains underexplored but may span gut barrier dysfunction, enteric glial targeting, mucosal immune dysregulation, and autoimmune targets within the enteric nervous system (ENS).
Federico Montini   +4 more
wiley   +1 more source

How much do delayed healthcare seeking, delayed care provision, and diversion from primary care contribute to the transmission of STIs? [PDF]

open access: yes, 2007
Objectives: To quantify the contribution of patient delay, provider delay, and diversion between services to delayed access to genitourinary medicine (GUM) clinics. To describe the factors associated with delay, and their contribution to STI transmission.
Cassell, JA   +44 more
core   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

open access: yesAnimal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang   +10 more
wiley   +1 more source

Complete labial fusion causing pseudo-urinary incontinence: A long-term sequelae of genitourinary syndrome

open access: yesJournal of Mid-Life Health, 2020
Genitourinary syndrome (GSM) of menopause is due to hypoestrogenism affecting the vagina and lower urinary tract. Atrophic changes manifesting as complete labial fusion (CLF) are rare.
Tanvir Tanvir   +2 more
doaj   +1 more source

The oral mucosal and salivary microbial community of Behçet's syndrome and recurrent aphthous stomatitis. [PDF]

open access: yes, 2015
This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is ...
Bergmeier, LA   +9 more
core   +1 more source

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