Results 1 to 10 of about 3,974,459 (404)

GenomeFingerprinter and universal genome fingerprint analysis for systematic comparative genomics [PDF]

, 2013
How to compare whole genome sequences at large scale has not been achieved via conventional methods based on pair-wisely base-to-base comparison; nevertheless, no attention was paid to handle in-one-sitting a number of genomes crossing genetic category (chromosome, plasmid, and phage) with farther divergences (much less or no homologous) over large ...
Ai, Hannan, Ai, Yuncan, Meng, Fanmei, Zhao, Lei   +3 more
arxiv   +6 more sources

Progressive Mauve: Multiple alignment of genomes with gene flux and rearrangement [PDF]

arXiv, 2009
Multiple genome alignment remains a challenging problem. Effects of recombination including rearrangement, segmental duplication, gain, and loss can create a mosaic pattern of homology even among closely related organisms. We describe a method to align two or more genomes that have undergone large-scale recombination, particularly genomes that have ...
Darling, Aaron E., Mau, Bob, Perna, Nicole T.   +2 more
arxiv   +3 more sources

Development and performance evaluation of an artificial intelligence algorithm using cell-free DNA fragment distance for non-invasive prenatal testing (aiD-NIPT)

Frontiers in Genetics, 2022
With advances in next-generation sequencing technology, non-invasive prenatal testing (NIPT) has been widely implemented to detect fetal aneuploidies, including trisomy 21, 18, and 13 (T21, T18, and T13).
Junnam Lee, Junnam Lee, Sae-Mi Lee, Jin Mo Ahn, Tae-Rim Lee, Wan Kim, Eun-Hae Cho, Chang-Seok Ki   +7 more
doaj   +1 more source

The Gene Ontology's Reference Genome Project: a unified framework for functional annotation across species. [PDF]

PLoS Computational Biology, 2009
The Gene Ontology (GO) is a collaborative effort that provides structured vocabularies for annotating the molecular function, biological role, and cellular location of gene products in a highly systematic way and in a species-neutral manner with the aim ...
Reference Genome Group of the Gene Ontology Consortium
doaj   +1 more source

Pursuing Advances in DNA Sequencing Technology to Solve a Complex Genomic Jigsaw Puzzle: The Agglutinin-Like Sequence (ALS) Genes of Candida tropicalis

Frontiers in Microbiology, 2021
The agglutinin-like sequence (ALS) gene family encodes cell-surface adhesins that interact with host and abiotic surfaces, promoting colonization by opportunistic fungal pathogens such as Candida tropicalis.
Soon-Hwan Oh, Allyson Isenhower, Rubi Rodriguez-Bobadilla, Brooke Smith, Jillian Jones, Vit Hubka, Vit Hubka, Christopher Fields, Alvaro Hernandez, Lois L. Hoyer   +9 more
doaj   +1 more source

First Characterization of a Hafnia Phage Reveals Extraordinarily Large Burst Size and Unusual Plaque Polymorphism

Frontiers in Microbiology, 2022
A unique lytic phage infecting Hafnia paralvei was isolated and identified. Hafnia phage Ca belongs to the family Autographiviridae, possessing an icosahedral head with a diameter of 55 nm and a short non-contractile tail.
Lingting Pan, Lingting Pan, Dengfeng Li, Zhitong Sun, Wei Lin, Wei Lin, Binxin Hong, Weinan Qin, Lihua Xu, Wencai Liu, Qin Zhou, Fei Wang, Ruqian Cai, Minhua Qian, Yigang Tong   +14 more
doaj   +1 more source

Multi-angle meta-analysis of the gut microbiome in Autism Spectrum Disorder: a step toward understanding patient subgroups

Scientific Reports, 2022
Observational studies have shown that the composition of the human gut microbiome in children diagnosed with Autism Spectrum Disorder (ASD) differs significantly from that of their neurotypical (NT) counterparts.
Kiana A. West, Xiaochen Yin, Erica M. Rutherford, Brendan Wee, Jinlyung Choi, Brianna S. Chrisman, Kaiti L. Dunlap, Roberta L. Hannibal, Wiputra Hartono, Michelle Lin, Edward Raack, Kayleen Sabino, Yonggan Wu, Dennis P. Wall, Maude M. David, Karim Dabbagh, Todd Z. DeSantis, Shoko Iwai   +17 more
doaj   +1 more source

Nutrigenomics: The science of the 21st century [PDF]

Vojnosanitetski Pregled, 2011
nema
Stojanović Dušica, Marković Danica
doaj   +1 more source

Unicycler: Resolving bacterial genome assemblies from short and long sequencing reads

bioRxiv, 2016
The Illumina DNA sequencing platform generates accurate but short reads, which can be used to produce accurate but fragmented genome assemblies. Pacific Biosciences and Oxford Nanopore Technologies DNA sequencing platforms generate long reads that can ...
R. Wick, L. Judd, C. Gorrie, K. Holt
semanticscholar   +1 more source

Metabolism and signaling crosstalk in glioblastoma progression and therapy resistance

Molecular Oncology, EarlyView., 2023
Glioblastoma is one of the most lethal human cancers with no effective treatment nowadays. Here, we review the increasing amount of evidence supporting the connection between cell signaling deregulation and metabolic reprogramming as a key event in glioblastoma resistance to cancer therapy.
Laura Zarzuela, Raúl V. Durán, Mercedes Tomé   +2 more
wiley   +1 more source