Results 91 to 100 of about 353,350 (233)

Bacterial Genomics and Pathogen Evolution [PDF]

Cell, 2006
The availability of hundreds of bacterial genome sequences has altered the study of bacterial pathogenesis, affecting both design of experiments and analysis of results. Comparative genomics and genomic tools have been used to identify virulence factors and genes involved in environmental persistence of pathogens.
Raskin, David M., Seshadri, Rekha, Pukatzki, Stefan U., Mekalanos, John J.   +3 more
openaire   +2 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Development and validation of an rDNA operon based primer walking strategy applicable to de novo bacterial genome finishing.

Frontiers in Microbiology, 2015
Advances in sequencing technology have drastically increased the depth and feasibility of bacterial genome sequencing. However, little information is available that details the specific techniques and procedures employed during genome sequencing despite ...
Alexander William Eastman, Alexander William Eastman, Ze-Chun eYuan, Ze-Chun eYuan   +3 more
doaj   +1 more source

Automated design of bacterial genome sequences [PDF]

, 2013
Background: Organisms have evolved ways of regulating transcription to better adapt to varying environments. Could the current functional genomics data and models support the possibility of engineering a genome with completely rearranged gene ...
Carrera, Javier, Jaramillo, Alfonso
core   +4 more sources

Bacterial genome encoded ParMs

Journal of Biological Chemistry
AbstractParMs generally exist on low copy number plasmids where they contribute to plasmid segregation and stable inheritance. We carried out bioinformatics analysis, which indicated that ParM genes are not only confined to plasmids but are also occasionally found on genomes.
Samson Ali, Adrian Koh, David Popp, Kotaro Tanaka, Yoshihito Kitaoku, Naoyuki Miyazaki, Kenji Iwasaki, Kaoru Mitsuoka, Robert C. Robinson, Akihiro Narita   +9 more
openaire   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Whole-genome sequencing in bacteriology: state of the art

Infection and Drug Resistance, 2013
Michael J DarkDepartment of Infectious Diseases and Pathology and Emerging Pathogens Institute, University of Florida, Gainesville, FL, USAAbstract: Over the last ten years, genome sequencing capabilities have expanded exponentially.
Dark MJ
doaj  

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Dynamics of genome rearrangement in bacterial populations.

PLoS Genetics, 2008
Genome structure variation has profound impacts on phenotype in organisms ranging from microbes to humans, yet little is known about how natural selection acts on genome arrangement.
Aaron E Darling, István Miklós, Mark A Ragan   +2 more
doaj   +1 more source