Results 101 to 110 of about 2,069,635 (294)

Comparison of the DNBSEQ platform and Illumina HiSeq 2000 for bacterial genome assembly

Scientific Reports
The Illumina HiSeq platform has been a commonly used option for bacterial genome sequencing. Now the BGI DNA nanoball (DNB) nanoarrays platform may provide an alternative platform for sequencing of bacterial genomes.
Tongyuan Hu, Jianwei Chen, Xiaoqian Lin, Wenxin He, Hewei Liang, Mengmeng Wang, Wenxi Li, Zhinan Wu, Mo Han, Xin Jin, Karsten Kristiansen, Liang Xiao, Yuanqiang Zou   +12 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Bacterial Genomes and Infectious Diseases [PDF]

Pediatric Research, 2003
The genome sequencing approach has proved to be highly effective and invaluable for gaining an insight on structure of bacteria genomes and the biology and evolution of bacteria. The diversity of bacteria genomes is beyond expectation. Gaining a full understanding of the biology and pathogenic mechanisms of these pathogens will be a major task because ...
openaire   +2 more sources

Development and validation of an rDNA operon based primer walking strategy applicable to de novo bacterial genome finishing.

Frontiers in Microbiology, 2015
Advances in sequencing technology have drastically increased the depth and feasibility of bacterial genome sequencing. However, little information is available that details the specific techniques and procedures employed during genome sequencing despite ...
Alexander William Eastman, Alexander William Eastman, Ze-Chun eYuan, Ze-Chun eYuan   +3 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Draft genome sequence of the Daphnia pathogen Octosporea bayeri: insights into the gene content of a large microsporidian genome and a model for host-parasite interactions [PDF]

, 2009
Background: The highly compacted 2.9-Mb genome of Encephalitozoon cuniculi placed the microsporidia in the spotlight, encoding a mere 2,000 proteins and a highly reduced suite of biochemical pathways.
Ebert, Dieter, Corradi, N., Pombert, J. F., Haag, Karen L., Keeling, P. J., Haag, Karen Luisa, Haag, K. L., Pombert, Jean-François, Corradi, Nicolas, Keeling, Patrick J., Keeling, Patrick J. (Patrick John), 1969-   +10 more
core   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

The Janthinobacterium sp. HH01 genome encodes a homologue of the V. cholerae CqsA and L. pneumophila LqsA autoinducer synthases. [PDF]

, 2013
Janthinobacteria commonly form biofilms on eukaryotic hosts and are known to synthesize antibacterial and antifungal compounds. Janthinobacterium sp. HH01 was recently isolated from an aquatic environment and its genome sequence was established.
Blokesch, Melanie, Kirsten Jung, Bode, E., Dierking, Katja, Hinrich Schulenburg, Andreas Bonge (279782), Schmeisser, Christel, Bode, Edna, Laure Plener, Frederike S. Haack (279780), Bonge, Andreas, Haack, Frederike Svenja, Spieck, Eva, Bode, Helge Björn, Dierking, K., Edna Bode (195835), Pommerening-Roeser, Andreas, Schulenburg, Hinrich, Anja Poehlein, Andrea Pohlen, Ines Krohn-Molt, Wolfgang R Streit, Eva Spieck, Andreas Pommerening-Röser (279786), Timmermann, G., Melanie Blokesch, Kirsten Jung (256459), Bode, H., Schmidt, Martina, Katja Dierking (199184), Spieck, E., Andreas Bonge, Melanie Blokesch (106198), Helge B. Bode (195839), Streit, Wolfgang R., Claudia Hornung, Christel Schmeisser (125567), Pommerening-Röser, Andreas, Daniel, R., Plener, Laure, Katja Dierking, Andrea Pohlen (279781), Gabriele Timmermann (279784), Hornung, C., Krohn-Molt, Ines, Poehlein, Anja, Jung, Kirsten, Utpatel, C., Eva Spieck (279785), Plener, L., Utpatel, Christian, Krohn-Molt, I., Rolf Daniel (113374), Christian Utpatel, Gabriele Timmermann, Ines Krohn-Molt (279783), Schmeisser, C., Bode, Helge B., Martina Schmidt (183309), Haack, F., Schmidt, M., Bonge, A., Streit, W., Haack, Frederike S., Andreas Pommerening-Röser, Jung, K., Hornung, Claudia, Frederike S Haack, Edna Bode, Rolf Daniel, Timmermann, Gabriele, Daniel, Rolf, Hinrich Schulenburg (74712), Helge B Bode, Christian Utpatel (199158), Wolfgang R. Streit (125596), Pommerening-Roeser, A., Anja Poehlein (113372), Laure Plener (164731), Blokesch, M., Poehlein, A., Claudia Hornung (199168), Martina Schmidt, Pohlen, A., Pohlen, Andrea, Christel Schmeisser, Schulenburg, H.   +86 more
core   +2 more sources

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Dynamics of genome rearrangement in bacterial populations.

PLoS Genetics, 2008
Genome structure variation has profound impacts on phenotype in organisms ranging from microbes to humans, yet little is known about how natural selection acts on genome arrangement.
Aaron E Darling, István Miklós, Mark A Ragan   +2 more
doaj   +1 more source