Results 91 to 100 of about 772,345 (307)

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Bacterial genome size and gene functional diversity negatively correlate with taxonomic diversity along a pH gradient

Nature Communications, 2023
Bacterial gene repertoires reflect adaptive strategies, contribute to ecosystem functioning and are limited by genome size. However, gene functional diversity does not necessarily correlate with taxonomic diversity because average genome size may vary by
Cong Wang, Qing-Yi Yu, Niu-Niu Ji, Yong Zheng, John W. Taylor, Liang-Dong Guo, Cheng Gao   +6 more
doaj   +1 more source

Cocirculation of Hajj and non-Hajj strains among serogroup W meningococci in Italy, 2000 to 2016 [PDF]

, 2019
In Italy, B and C are the predominant serogroups among meningococci causing invasive diseases. Nevertheless, in the period from 2013 to 2016, an increase in serogroup W Neisseria meningitidis (MenW) was observed.
Arghittu M., Barbui A. M., Bernaschi P., Bisbano A., Chironna M., Ciammaruconi A., De Nittis R., Fazio C., Galanti I. A., Giammanco A., Isola P., Mencacci A., Neri A., Pagani E., Stefanelli P., Vacca P., Vocale C.   +16 more
core   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Campylobacter species in dogs and cats and significance to public health in New Zealand : a thesis in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Science at Massey University, Palmerston North, New Zealand [PDF]

, 2016
Campylobacter spp. are a major cause of bacterial gastroenteritis in people in the developed world, including New Zealand. Many sources and transmission routes exist, as these bacteria are common in animals and the environment. C.
Bojanić, Krunoslav
core  

Evolution of plant ribosome-inactivating proteins [PDF]

, 2010
This contribution presents an updated analysis of the evolution of ribosome-inactivating proteins (RIPs) in plants. All evidence suggests that an ancestor of modern seed plants developed the RIP domain at least 300 million years ago.
Peumans, Willy J, Van Damme, Els
core   +1 more source

Bacterial Genomics and Pathogen Evolution [PDF]

Cell, 2006
The availability of hundreds of bacterial genome sequences has altered the study of bacterial pathogenesis, affecting both design of experiments and analysis of results. Comparative genomics and genomic tools have been used to identify virulence factors and genes involved in environmental persistence of pathogens.
Raskin, David M., Seshadri, Rekha, Pukatzki, Stefan U., Mekalanos, John J.   +3 more
openaire   +2 more sources

Plant‐Produced Viral Nanoparticles Decorated with Nanobodies Against HER2 Improve Retention and Recruitment of Immune Cells in Solid Tumors

Advanced Healthcare Materials, EarlyView.
Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez, Miguel A. Moreno‐Gonzalez, Fernando Merwaiss, Nicole F. Steinmetz, José‐Antonio Daròs   +4 more
wiley   +1 more source

Comparison of the DNBSEQ platform and Illumina HiSeq 2000 for bacterial genome assembly

Scientific Reports
The Illumina HiSeq platform has been a commonly used option for bacterial genome sequencing. Now the BGI DNA nanoball (DNB) nanoarrays platform may provide an alternative platform for sequencing of bacterial genomes.
Tongyuan Hu, Jianwei Chen, Xiaoqian Lin, Wenxin He, Hewei Liang, Mengmeng Wang, Wenxi Li, Zhinan Wu, Mo Han, Xin Jin, Karsten Kristiansen, Liang Xiao, Yuanqiang Zou   +12 more
doaj   +1 more source

Systematic determination of the mosaic structure of bacterial genomes: species backbone versus strain-specific loops

BMC Bioinformatics, 2005
Background Public databases now contain multitude of complete bacterial genomes, including several genomes of the same species. The available data offers new opportunities to address questions about bacterial genome evolution, a task that requires ...
Gendrault-Jacquemard A, Heuclin G, Sourivong F, Bourgait I, Chiapello H, Petit M-A, El Karoui M   +6 more
doaj   +1 more source