Results 121 to 130 of about 2,069,635 (294)

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Genomics and the bacterial species problem.

Genome biology, 2006
Whether or not bacteria have species is a perennially vexatious question. Given what we now know about variation among bacterial genomes, we argue that there is no intrinsic reason why the processes driving diversification and adaptation must produce groups of individuals sufficiently coherent in their genetic and phenotypic properties to merit the ...
Doolittle, W Ford, Papke, R Thane
openaire   +2 more sources

Complete genome sequence and lifestyle of black-pigmented Corynebacterium aurimucosum ATCC 700975 (formerly C. nigricans CN-1) isolated from a vaginal swab of a woman with spontaneous abortion [PDF]

, 2010
Trost E, Götker S, Schneider J, et al. Complete genome sequence and lifestyle of black-pigmented Corynebacterium aurimucosum ATCC 700975 (formerly C. nigricans CN-1) isolated from a vaginal swab of a woman with spontaneous abortion. BMC Genomics. 2010;11(
Szczepanowski, Rafael, Karl-Heinz Gartemann, Viehöver, Prisca, Arnold, Walter, Jochen Blom, Trost, Eva ; https://orcid.org/, Goesmann, Alexander ; https://orcid.org/, Thomas Bekel, Shukla, Sanjay K., Tilker, Alexandra, Gartemann, Karl-Heinz ; https://orcid.org/, Schneider, Jessica, Alfred Pühler, Alexander Goesmann, Blom, Jochen, Walter Arnold, Susanne Götker, Jessica Schneider, Andreas Tauch, Linke, Burkhard, Schneiker-Bekel, Susanne, Bekel, Thomas, Eva Trost, Pühler, Alfred ; https://orcid.org/, Götker, Susanne, Susanne Schneiker-Bekel, Rafael Szczepanowski, Burkhard Linke, Sanjay K Shukla, Tauch, Andreas, Alexandra Tilker, Prisca Viehoever   +31 more
core   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Genome sequence of Rhodobacter sphaeroides strain WS8N [PDF]

, 2011
Copyright © 2011, American Society for MicrobiologyRhodobacter sphaeroides is a metabolically diverse photosynthetic alphaproteobacterium found ubiquitously in soil and freshwater habitats. Here we present the annotated genome sequence of R.
Byles, ED, Elaine D. Byles, Judith P. Armitage, George H. Wadhams, Armitage, JP, Taylor, Stephen, Taylor, S, Wadhams, GH, Wadhams, George, Saunders, NJ, Steven L. Porter, Stephen Taylor, Armitage, Judith, Nigel J. Saunders, Wilkinson, DA, Porter, SL, David A. Wilkinson   +16 more
core   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Artificial Activation of Escherichia coli mazEF and hipBA Toxin–Antitoxin Systems by Antisense Peptide Nucleic Acids as an Antibacterial Strategy

Frontiers in Microbiology, 2018
The search for new, non-standard targets is currently a high priority in the design of new antibacterial compounds. Bacterial toxin–antitoxin systems (TAs) are genetic modules that encode a toxin protein that causes growth arrest by interfering with ...
Marcin Równicki, Marcin Równicki, Tomasz Pieńko, Tomasz Pieńko, Jakub Czarnecki, Jakub Czarnecki, Monika Kolanowska, Monika Kolanowska, Dariusz Bartosik, Joanna Trylska   +9 more
doaj   +1 more source

Bacterial Genomes

In Bacterial Genomes, the evolutionary and regulatory processes that shape bacterial life are brought to life. This textbook offers a conceptual exploration of how bacterial genomes are organized, how they evolve, and how their genetic information is interpreted through intricate molecular networks.
openaire   +3 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Physical mapping of bacterial genomes

Journal of Bacteriology, 1995
The elucidation of gene order in chromosomes, influencing both linkage and coregulation, is at the heart of genetic analysis. Indeed, the characterization of any mutation or cloned gene traditionally includes the determination of its position on the chromosomal map.
M, Fonstein, R, Haselkorn
openaire   +3 more sources