Results 141 to 150 of about 2,805,364 (358)

Dynamics of genome rearrangement in bacterial populations.

open access: yesPLoS Genetics, 2008
Genome structure variation has profound impacts on phenotype in organisms ranging from microbes to humans, yet little is known about how natural selection acts on genome arrangement.
Aaron E Darling   +2 more
doaj   +1 more source

Prophages in Salmonella enterica: a driving force in reshaping the genome and physiology of their bacterial host?

open access: yesMolecular Microbiology, 2018
Thanks to the exponentially increasing number of publicly available bacterial genome sequences, one can now estimate the important contribution of integrated viral sequences to the diversity of bacterial genomes. Indeed, temperate bacteriophages are able
Astrid Wahl   +2 more
semanticscholar   +1 more source

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino   +12 more
wiley   +1 more source

3D‐Printed Piezoionic/Bioelectronic Hydrogel for Electro‐Metabolic Regulation of Osteogenic Differentiation

open access: yesAdvanced Healthcare Materials, EarlyView.
A 3D‐printed piezoionic GPMx hydrogel enables stable electromechanical signal generation under mechanical loading, exhibiting long‐term durability and low fatigue. As a bioactive patch, it restores endogenous bioelectricity to stimulate osteogenesis via Ca2+ influx and mitochondrial activation, while simultaneously enabling label‐free alkaline ...
Sayan Deb Dutta   +3 more
wiley   +1 more source

Roary : rapid large-scale prokaryote pan genome analysis

open access: yes, 2015
This work was supported by the Wellcome Trust (grant WT 098051).A typical prokaryote population sequencing study can now consist of hundreds or thousands of isolates.
Page, Andrew J   +9 more
core   +1 more source

Structure of a trimeric bacterial microcompartment shell protein, EtuB, associated with ethanol utilization inClostridium kluyveri [PDF]

open access: yes, 2009
It has been suggested that ethanol metabolism in the strict anaerobe Clostridium kluyveri occurs within a metabolosome, a subcellular proteinaceous bacterial microcompartment. Two bacterial microcompartment shell proteins [EtuA (ethanol utilization shell
Seyedarabi, Arefeh   +10 more
core   +1 more source

Genomics and the bacterial species problem.

open access: yesGenome biology, 2006
Whether or not bacteria have species is a perennially vexatious question. Given what we now know about variation among bacterial genomes, we argue that there is no intrinsic reason why the processes driving diversification and adaptation must produce groups of individuals sufficiently coherent in their genetic and phenotypic properties to merit the ...
Doolittle, W Ford, Papke, R Thane
openaire   +2 more sources

Characterizing a thermostable Cas9 for bacterial genome editing and silencing

open access: yesbioRxiv, 2017
CRISPR-Cas9-based genome engineering tools have revolutionized fundamental research and biotechnological exploitation of both eukaryotes and prokaryotes.
Ioannis Mougiakos   +9 more
semanticscholar   +1 more source

Seta‐Inspired Mechano‐Intelligent Janus Bandage with Coordinated Adhesion–Contraction for Minimizing Scarring

open access: yesAdvanced Materials, EarlyView.
We developed a bioinspired mechano‐intelligent Janus bandage (MIB) with a hydrophobic flat exterior and a hydrophilic interior featuring gecko‐mimicking wedged microstructures, fabricated via micromolding and anisotropic plasma treatment. The MIB dynamically synchronizes adhesion and contraction, enabling precise force modulation.
Di Suo   +7 more
wiley   +1 more source

ClustAGE: a tool for clustering and distribution analysis of bacterial accessory genomic elements

open access: yesBMC Bioinformatics, 2018
Background The non-conserved accessory genome of bacteria can be associated with important adaptive characteristics that can contribute to niche specificity or pathogenicity of strains.
Egon A. Ozer
doaj   +1 more source

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