Results 141 to 150 of about 717,916 (306)
A Markovian genomic concatenation model guided by persymmetric matrices [PDF]
The aim of this work is to provide a rigorous mathematical analysis of a stochastic concatenation model presented by Sobottka and Hart (2011) which allows approximation of the first-order stochastic structure in bacterial DNA by means of a stationary Markov chain.
arxiv
Trait‐Based Life History Strategies Shape Bacterial Niche Breadth
This study investigates bacterial niche breadth through a large‐scale soil survey and over 2000 bacterial genomes. It identifies key life‐history traits—growth, competition, stress tolerance, resource acquisition, and dispersal—that correlate with niche breadth.
Ziheng Peng+8 more
wiley +1 more source
Bio-Communication of Bacteria and its Evolutionary Interrelations to Natural Genome Editing Competences of Viruses [PDF]
Communicative competences enable bacteria to develop, organise and coordinate rich social life with a great variety of behavioral patterns even in which they organise themselves like multicellular organisms.
Guenther Witzany
core +2 more sources
Genomics and the bacterial species problem.
Whether or not bacteria have species is a perennially vexatious question. Given what we now know about variation among bacterial genomes, we argue that there is no intrinsic reason why the processes driving diversification and adaptation must produce groups of individuals sufficiently coherent in their genetic and phenotypic properties to merit the ...
R. Thane Papke, W. Ford Doolittle
openaire +3 more sources
Self‐Adjusting Engineered Probiotic for Targeted Tumor Colonization and Local Therapeutics Delivery
Zou et al. developed an engineered strain of Escherichia coli Nissle 1917 with precise targeting abilities for colonization and on‐demand payload release. The engineered probiotic survives and embolizes tumors only in the presence of more than 5 mM L‐lactate. Furthermore, the introduction of an α‐hemolysin circuit enhances its anti‐tumor effect.
Zhen‐Ping Zou+8 more
wiley +1 more source
Why genes evolve faster on secondary chromosomes in bacteria [PDF]
In bacterial genomes composed of more than one chromosome, one replicon is typically larger, harbors more essential genes than the others, and is considered primary.
Cooper, Vaughn S.+3 more
core +1 more source
Iron deficiency reduces monocyte dendritic cell progenitor (MDP) numbers by inhibiting migration and proliferation while promoting apoptosis, subsequently reducing downstream common dendritic cell precursors (CDP) and dendritic cell (DC). Impaired DCs enter the lungs via blood circulation, where reduced antigen presentation impairs T‐cell activation ...
Quanzhong Ren+8 more
wiley +1 more source
A non-canonical mismatch repair pathway in prokaryotes
Despite the importance of mismatch repair for genome stability, many Archaea and almost all Actinobacteria lack MutS and MutL proteins. Here the authors, usingMycobacterium smegmatisas a model, report that NucS/EndoMS endonuclease acts in a distinct ...
A. Castañeda-García+16 more
doaj +1 more source
This study explores the structural heterogeneity and evolutionary adaptations of heteromultimeric bacterioferritins. Hetero‐Bfrs, evolved from either a homo‐Bfr or Ftn by gene duplications, differ from homo‐Bfrs substantially in the mechanisms underpinning iron oxidation and reduction despite high similarity in overall structure.
Yingxi Li+5 more
wiley +1 more source
Towards a balanced view of the bacterial tree of life
The bacterial tree of life has recently undergone significant expansion, chiefly from candidate phyla retrieved through genome-resolved metagenomics. Bypassing the need for genome availability, we present a snapshot of bacterial phylogenetic diversity ...
Frederik Schulz+7 more
doaj +1 more source