Results 31 to 40 of about 353,350 (233)

Quantitative Proteome Profiling of Coxiella burnetii Reveals Major Metabolic and Stress Differences Under Axenic and Cell Culture Cultivation

open access: yesFrontiers in Microbiology, 2019
Coxiella burnetii is the causative agent of the zoonotic disease Q fever. To date, the lipopolysaccharide (LPS) is the only defined and characterized virulence determinant of C. burnetii. In this study, proteome profiles of C. burnetii Nine Mile phase I (
Jiri Dresler   +8 more
doaj   +1 more source

Genomic blueprints of sponge-prokaryote symbiosis are shared by low abundant and cultivatable Alphaproteobacteria [PDF]

open access: yes, 2019
Marine sponges are early-branching, filter-feeding metazoans that usually host complex microbiomes comprised of several, currently uncultivatable symbiotic lineages.
Cox, Cymon   +6 more
core   +4 more sources

Reduced mutation rate and increased transformability of transposon-free Acinetobacter baylyi ADP1-ISx [PDF]

open access: yes, 2017
The genomes of most bacteria contain mobile DNA elements that can contribute to undesirable genetic instability in engineered cells. In particular, transposable insertion sequence (IS) elements can rapidly inactivate genes that are important for a ...
Barrick, Jeffrey E   +3 more
core   +2 more sources

Consistent Metagenome-Derived Metrics Verify and Delineate Bacterial Species Boundaries

open access: yesmSystems, 2020
Longstanding questions relate to the existence of naturally distinct bacterial species and genetic approaches to distinguish them. Bacterial genomes in public databases form distinct groups, but these databases are subject to isolation and deposition ...
Matthew R. Olm   +5 more
doaj   +3 more sources

Comparative genomics of Shiga toxin encoding bacteriophages [PDF]

open access: yes, 2012
Background Stx bacteriophages are responsible for driving the dissemination of Stx toxin genes (stx) across their bacterial host range. Lysogens carrying Stx phages can cause severe, lifethreatening disease and Stx toxin is an integral virulence factor.
Allison, Heather   +6 more
core   +2 more sources

Bacterial Genomes: Habitat Specificity and Uncharted Organisms [PDF]

open access: yesMicrobial Ecology, 2012
The capability and speed in generating genomic data have increased profoundly since the release of the draft human genome in 2000. Additionally, sequencing costs have continued to plummet as the next generation of highly efficient sequencing technologies (next-generation sequencing) became available and commercial facilities promote market competition.
Dini-Andreote, Francisco   +4 more
openaire   +3 more sources

The Most Frequently Used Sequencing Technologies and Assembly Methods in Different Time Segments of the Bacterial Surveillance and RefSeq Genome Databases

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Whole genome sequencing has become a powerful tool in modern microbiology. Especially bacterial genomes are sequenced in high numbers. Whole genome sequencing is not only used in research projects, but also in surveillance projects and outbreak ...
Bo Segerman, Bo Segerman
doaj   +1 more source

Genome-wide detection of spontaneous chromosomal rearrangements in bacteria. [PDF]

open access: yesPLoS ONE, 2012
Genome rearrangements have important effects on bacterial phenotypes and influence the evolution of bacterial genomes. Conventional strategies for characterizing rearrangements in bacterial genomes rely on comparisons of sequenced genomes from related ...
Song Sun   +4 more
doaj   +1 more source

Bacterial microevolution and the Pangenome [PDF]

open access: yes, 2020
The comparison of multiple genome sequences sampled from a bacterial population reveals considerable diversity in both the core and the accessory parts of the pangenome.
A Bankevich   +68 more
core   +1 more source

Genomics and Bacterial Pathogenesis [PDF]

open access: yesEmerging Infectious Diseases, 2000
Whole-genome sequencing is transforming the study of pathogenic bacteria. Searches for single virulence genes can now be performed on a genomewide scale by a variety of computer and genetic techniques. These techniques are discussed to provide a perspective on the developing field of genomics.
openaire   +3 more sources

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