Results 41 to 50 of about 717,916 (306)

Quantitative Proteome Profiling of Coxiella burnetii Reveals Major Metabolic and Stress Differences Under Axenic and Cell Culture Cultivation

Frontiers in Microbiology, 2019
Coxiella burnetii is the causative agent of the zoonotic disease Q fever. To date, the lipopolysaccharide (LPS) is the only defined and characterized virulence determinant of C. burnetii. In this study, proteome profiles of C. burnetii Nine Mile phase I (
Jiri Dresler, Jana Klimentova, Petr Pajer, Barbora Salovska, Alena Myslivcova Fucikova, Martin Chmel, Gernot Schmoock, Heinrich Neubauer, Katja Mertens-Scholz   +8 more
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Genomics and Bacterial Metabolism [PDF]

Current Issues in Molecular Biology, 2003
The field of bacterial metabolism and physiology is arguably the oldest in microbiology. Much of our understanding of biological processes and molecular paradigms has its roots In early studies of prokaryotic physiology. After a period of declining interest in metabolic studies (prompted by the insurgence of molecular techniques), genomic technologies ...
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The automatic annotation of bacterial genomes [PDF]

Briefings in Bioinformatics, 2012
With the development of ultra-high-throughput technologies, the cost of sequencing bacterial genomes has been vastly reduced. As more genomes are sequenced, less time can be spent manually annotating those genomes, resulting in an increased reliance on automatic annotation pipelines. However, automatic pipelines can produce inaccurate genome annotation
Richardson, Emily, Watson, Mick
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Consistent Metagenome-Derived Metrics Verify and Delineate Bacterial Species Boundaries

mSystems, 2020
Longstanding questions relate to the existence of naturally distinct bacterial species and genetic approaches to distinguish them. Bacterial genomes in public databases form distinct groups, but these databases are subject to isolation and deposition ...
Matthew R. Olm, Alexander Crits-Christoph, Spencer Diamond, Adi Lavy, Paula B. Matheus Carnevali, Jillian F. Banfield   +5 more
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Population gene introgression and high genome plasticity for the zoonotic pathogen Streptococcus agalactiae [PDF]

, 2019
The influence that bacterial adaptation (or niche partitioning) within species has on gene spillover and transmission among bacteria populations occupying different niches is not well understood.
Abbott, Abby, Almeida, Baily, Bankevich, Beerli, Beerli, Benjamini, Bertels, Bikard, Bisharat, Bishop, Bohnsack, Borchardt, Brett M Probert, Brochet, Bruen, Brynildsrud, Capella-Gutierrez, Chen, Chen, Cheng, Chiara Crestani, Chopra, Christopher D Town, Conrad, Croucher, Da Cunha, Delannoy, Delannoy, Dogan, Edgar, Enright, Erwin, Fernandez, Ferreira, Flores, Fluegge, Garrett H Springer, Gauthier, Glazko, Glazko, Greig, Guglielmini, Gupta, Hayley B Hassler, Heaps, Holt, Imperi, Inouye, Irina M Velsko, Jafar, Jaskowiak, Jeukens, Johri, Jones, Jones, Jorgensen, Joubrel, Kalimuddin, Kim, Konig, Langdon, Librado, Lin, Lindahl, Liu, Liu, Lopez-Sanchez, Loytynoja, Lyhs, Manning, Manning, Martins, Marttinen, Mather, McArthur, Md Tauqeer Alam, Michael J Stanhope, Morse, Murrell, Page, Pal, Paulina D Pavinski Bitar, Pedersen, Petrovska, Pond, Poyart, Price, Qin, Richards, Richards, Richards, Rosinski-Chupin, Ruth N Zadoks, Sahl, Sahl, Sahl, Scheffer, Schrieber, Seemann, Shannon D Manning, Shapiro, Shepheard, Sheppard, Spoor, Springman, Srivastava, Stamatakis, Stoddard, Sukhnanand, Supek, Tettelin, Tettelin, Tian, van der Mee-Marquet, Verani, Viana, Vincent P Richards, Yu, Zadoks, Zankari, Zerbino, Zhang, Zhu   +124 more
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Bacterial Genomics and Pathogen Evolution [PDF]

Cell, 2006
The availability of hundreds of bacterial genome sequences has altered the study of bacterial pathogenesis, affecting both design of experiments and analysis of results. Comparative genomics and genomic tools have been used to identify virulence factors and genes involved in environmental persistence of pathogens.
Stefan Pukatzki, Rekha Seshadri, David M. Raskin, John J. Mekalanos   +3 more
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SIMBA: a web tool for managing bacterial genome assembly generated by Ion PGM sequencing technology [PDF]

, 2016
Background The evolution of Next-Generation Sequencing (NGS) has considerably reduced the cost per sequenced-base, allowing a significant rise of sequencing projects, mainly in prokaryotes. However, the range of available NGS platforms requires different
Aguiar, Edgar L., Azevedo, Vasco A. C., Barh, Debmalya, Benevides, Leandro, Figueiredo, Henrique C. P., Folador, Edson L., Ghosh, Preetam, Guimarães, Luís C., Mariano, Diego C. B., Oliveira, Letícia C., Pereira, Felipe L., Ramos, Rommel T. J., Silva, Artur, Sousa, Thiago J.   +13 more
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Sequencing and analysis of bacterial genomes [PDF]

Current Biology, 1996
The complete sequences of two small bacterial genomes have recently become available, and those of several more species should follow within the next two years. Sequence comparisons show that the most bacterial proteins are highly conserved in evolution, allowing predictions to be made about the functions of most products of an uncharacterized genome ...
Kenneth E. Rudd, Eugene V. Koonin, Arcady Mushegian   +2 more
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The Most Frequently Used Sequencing Technologies and Assembly Methods in Different Time Segments of the Bacterial Surveillance and RefSeq Genome Databases

Frontiers in Cellular and Infection Microbiology, 2020
Whole genome sequencing has become a powerful tool in modern microbiology. Especially bacterial genomes are sequenced in high numbers. Whole genome sequencing is not only used in research projects, but also in surveillance projects and outbreak ...
Bo Segerman, Bo Segerman
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Genome-wide detection of spontaneous chromosomal rearrangements in bacteria. [PDF]

PLoS ONE, 2012
Genome rearrangements have important effects on bacterial phenotypes and influence the evolution of bacterial genomes. Conventional strategies for characterizing rearrangements in bacterial genomes rely on comparisons of sequenced genomes from related ...
Song Sun, Rongqin Ke, Diarmaid Hughes, Mats Nilsson, Dan I Andersson   +4 more
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