Results 41 to 50 of about 760,059 (282)
The emergence and fate of horizontally acquired genes in Escherichia coli [PDF]
Bacterial species, and even strains within species, can vary greatly in their gene contents and metabolic capabilities. We examine the evolution of this diversity by assessing the distribution and ancestry of each gene in 13 sequenced isolates of ...
Marri, P.R. +2 more
core +4 more sources
The automatic annotation of bacterial genomes [PDF]
With the development of ultra-high-throughput technologies, the cost of sequencing bacterial genomes has been vastly reduced. As more genomes are sequenced, less time can be spent manually annotating those genomes, resulting in an increased reliance on automatic annotation pipelines. However, automatic pipelines can produce inaccurate genome annotation
Richardson, Emily, Watson, Mick
openaire +3 more sources
Whole genome sequencing has become a powerful tool in modern microbiology. Especially bacterial genomes are sequenced in high numbers. Whole genome sequencing is not only used in research projects, but also in surveillance projects and outbreak ...
Bo Segerman, Bo Segerman
doaj +1 more source
Genome-wide detection of spontaneous chromosomal rearrangements in bacteria. [PDF]
Genome rearrangements have important effects on bacterial phenotypes and influence the evolution of bacterial genomes. Conventional strategies for characterizing rearrangements in bacterial genomes rely on comparisons of sequenced genomes from related ...
Song Sun +4 more
doaj +1 more source
The infinitely many genes model with horizontal gene transfer
The genome of bacterial species is much more flexible than that of eukaryotes. Moreover, the distributed genome hypothesis for bacteria states that the total number of genes present in a bacterial population is greater than the genome of every single ...
Baumdicker, Franz, Pfaffelhuber, Peter
core +1 more source
The influence of the accessory genome on bacterial pathogen evolution [PDF]
Bacterial pathogens exhibit significant variation in their genomic content of virulence factors. This reflects the abundance of strategies pathogens evolved to infect host organisms by suppressing host immunity.
Abu-Ali GS +120 more
core +2 more sources
Automated design of bacterial genome sequences [PDF]
Background: Organisms have evolved ways of regulating transcription to better adapt to varying environments. Could the current functional genomics data and models support the possibility of engineering a genome with completely rearranged gene ...
Carrera, Javier, Jaramillo, Alfonso
core +4 more sources
Failure of phylogeny inferred from multilocus sequence typing to represent bacterial phylogeny
Although multilocus sequence typing (MLST) is highly discriminatory and useful for outbreak investigations and epidemiological surveillance, it has always been controversial whether clustering and phylogeny inferred from the MLST gene loci can represent ...
Alan K. L. Tsang +4 more
doaj +1 more source
Discovery of thermophilic Bacillales using reduced-representation genotyping for identification
Background This study demonstrates the use of reduced-representation genotyping to provide preliminary identifications for thermophilic bacterial isolates.
Berenice Talamantes-Becerra +3 more
doaj +1 more source
Bacterial genome reductions: Tools, applications, and challenges
Bacterial cells are widely used to produce value-added products due to their versatility, ease of manipulation, and the abundance of genome engineering tools. However, the efficiency of producing these desired biomolecules is often hindered by the cells’
Nicole LeBlanc +2 more
doaj +1 more source

