Results 91 to 100 of about 9,417,161 (263)

The Capsaspora genome reveals a complex unicellular prehistory of animals [PDF]

, 2013
To reconstruct the evolutionary origin of multicellular animals from their unicellular ancestors, the genome sequences of diverse unicellular relatives are essential. However, only the genome of the choanoflagellate Monosiga brevicollis has been reported
Chen, Zehua, Kerner, Pierre, Ruiz-Trillo, Iñaki, Vervoort, Michel, Sánchez-Pons, Núria, Russ, Carsten, Kramer, Eric, Carr, Martin, Roger, Andrew J., Suga, Hiroshi, Nusbaum, Chad, de Mendoza, Alex, Haas, Brian J., Lang, B. Franz, Manning, Gerard, Sebé-Pedrós, Arnau, Torruella, Guifré, Derelle, Romain, Brown, Matthew W., Mendoza, Alex de   +19 more
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'Race' and the human genome [PDF]

Nature Genetics, 2004
This supplement has its origins on May 15, 2003, when the National Human Genome Center at Howard University held a small but important workshop in Washington DC. The workshop, Human Genome Variation and 'Race', and this special issue of Nature Genetics were proposed by scientists at Howard University and financially supported by the Genome Programs of ...
openaire   +2 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Justice and the human genome project

, 1994
The Human Genome Project is an expensive, ambitious, and controversial attempt to locate and map every one of the approximately 100,000 genes in the human body.
Murphy, Timothy F 1955-, Lappé, Marc, Human Genome Project., Human Genome Project   +3 more
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Functional analysis and transcriptional output of the Göttingen minipig genome [PDF]

, 2015
In the past decade the Göttingen minipig has gained increasing recognition as animal model in pharmaceutical and safety research because it recapitulates many aspects of human physiology and metabolism.
Isaac Lekolool (3417695), Ulrich Certa, Martin Ebeling (187407), Okoth, Edward, Ringshandl, Stephan, Bernd Kuhn (260084), Schmitt, Georg, Daubenberger, Claudia, Roger Pelle, Azinwi Phina Khan, Küng, Erich, Hamina Daff (2139655), Guido Steiner (72571), Lekolool, Isaac, Marco Berrera (82653), Erich Küng, Heckel, Tobias, Edward Okoth, Berrera, Marco, Khan, Azinwi Phina, Hamina Daff, Laura Badi (187411), Ulrich Certa (54734), Ebeling, Martin, Roland Schmucki (793618), Edward Okoth (734350), Stephan Ringshandl (3417686), Schmucki, Roland, Daff, Hamina, Certa, Ulrich, Nicole Kratochwil (2463565), Kiialainen, Anna, Claudia Daubenberger, Tobias Heckel (3417707), Bernd Kuhn, Richard Bishop (59737), Roger Pelle (59739), Richard Bishop, Anna Kiialainen, Morgane Ravon (3417692), Tobias Heckel, Corinne Nowaczyk (3417704), Steiner, Guido, Nicole A. Kratochwil, Georg Schmitt, Laura Badi, Georg Schmitt (3417689), Marco Berrera, Morgane Ravon, Anna Kiialainen (230525), Pelle, Roger, Nowaczyk, Corinne, Corinne Nowaczyk, Stephan Ringshandl, Erich KĂźng (3417734), Claudia Daubenberger (212658), Kratochwil, Nicole A., Guido Steiner, Ravon, Morgane, Bishop, Richard, Martin Ebeling, Azinwi Khan (3417698), Badi, Laura, Roland Schmucki, Isaac Lekolool, Kuhn, Bernd   +65 more
core   +1 more source

P035: Estimating the carrier frequency and prevalence of inborn errors of propionate and cobalamin metabolism using population databases

Genetics in Medicine Open, 2023
Jennifer Sloan, Irini Manoli, Charles Venditti   +2 more
doaj   +1 more source

Clinical and molecular characterization of an Egyptian cohort with autosomal recessive hypophosphatasia

Scientific Reports
Hypophosphatasia (HPP) is a rare inborn error of metabolism caused by pathogenic variants in the ALPL. Reduced alkaline phosphatase (ALP) activity impairs hydroxyapatite formation and thereby reduces skeletal mineralization.
Dina El Dessouki, Rasha M. Elhossini, Nehal F. Hassib, Sherif F. Abdel-Ghafar, Maha R. Abouzaid, Adel M. Ashour, Ghada A. Otaify, Mohamed S. Abdel-Hamid, Mona S. Aglan   +8 more
doaj   +1 more source

Changes in H3K27ac following lipopolysaccharide stimulation of nasopharyngeal epithelial cells

BMC Genomics, 2018
Background The epithelium is the first line of defense against pathogens. Notably the epithelial cells lining the respiratory track are crucial in sensing airborne microbes and mounting an effective immune response via the expression of target genes such
Lisa Borghini, Martin Hibberd, Sonia Davila   +2 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Legal Problems: Human Genome Project

, 1993
Conference on Legal Aspects of the Human Genome Project in Bilbao, Spain; May 24-26 ...
Kirby, Michael
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