Results 231 to 240 of about 2,058,071 (297)

O26: Analysis of patient-reported outcomes and a functional assessment from 3-year nitisinone treatment trial in patients with alkaptonuria

Genetics in Medicine Open
Kathryn Spears, Francis Rossignol, Monique Perry, Joy Bryant, William Gahl, Wendy Introne   +5 more
doaj   +1 more source

Biomimetic Copper‐Doped Nano‐Aluminum Adjuvant Potentiates Therapy in Chemoresistant Acute Myeloid Leukemia

Advanced Healthcare Materials, EarlyView.
We developed a novel copper‐doped aluminum nano‐adjuvant (CuNA) to overcome cytarabine resistance in acute myeloid leukemia (AML). CuNA effectively sensitizes drug‐resistant AML cells to cytarabine by inducing mitochondrial dysfunction and inhibiting HMGCR/GPX4 to amplify ferroptosis.
Chao He, Lingxiao Zhang, Yue Xiong, Yu Wang, Yuqing Zeng, Dandan Su, Ran Wang, Ying Li, Hongbo Chen, Fang Cheng, Zhi Ping Xu   +10 more
wiley   +1 more source

Genomic analysis of a clinical Streptococcus suis ST1 isolate from CSF reveals antimicrobial resistance, virulence, and an evolutionary link to ST7. [PDF]

Sci Rep
Jiang J, Duan W, Liang L.
europepmc   +1 more source

ETV2 Mediated Differentiation of Human Pluripotent Stem Cells Results in Functional Endothelial Cells for Engineering Advanced Vascularized Microphysiological Models

Advanced Healthcare Materials, EarlyView.
A robust method to generate functional human iPSC‐derived endothelial cells using inducible ETV2 expression. These cells self‐organize into stable, lumenized microvascular networks within microfluidic chips, surpassing conventional differentiation methods.
Shun Zhang, Zhengpeng Wan, Lei Wang, Caihong Wu, Junkai Zhang, Sarah Spitz, Xun Wang, Marie A. Floryan, Mark F. Coughlin, Francesca M. Pramotton, Liling Xu, Ron Weiss, Roger D. Kamm   +12 more
wiley   +1 more source

TaoChongBao: a large-scale <i>C. elegans</i> missense variant database bridging worm and human genomes. [PDF]

Life Sci Alliance
Li M, Wang S, Chai Y, Guo Z, Wang Z, Chen Z, Lei K, Ke J, Huang X, Chen G, Huang P, Xu K, Shen Z, Li W, Ou G.   +14 more
europepmc   +1 more source

Zimin patterns in genomes. [PDF]

PLoS Comput Biol
Chantzi N, Mouratidis I, Georgakopoulos-Soares I.   +2 more
europepmc   +1 more source

CRISPR-Cas9 engineering of CAR-T cells: Can non-viral nanoparticles unlock safer and scalable genome editing? [PDF]

iScience
My B, Lia A, Rizzo L, Maiorano G, Galeone A, Palamà IE, Gigli G.   +6 more
europepmc   +1 more source

Evolutionary and Mobile Genetic Element Analysis of a Multidrug-Resistant ST398-MRSA-Vc Isolate from Ready-to-Eat Pork Products. [PDF]

Antibiotics (Basel)
Wan J, Wang X, Wang K, Feng Q, Yuan R, Qi X, Lai Y, Yan H.   +7 more
europepmc   +1 more source

A Chromosome-level Assembly and Functional Genomic Resources for the Model Annelid Capitella teleta. [PDF]

Genome Biol Evol
Davies BE, Gonzalez P, Sur A, Wei J, Frankish T, Montagne J, Carrillo-Baltodano AM, Guynes K, Liang Y, Donnellan RD, Travis Moreland R, Singh S, Zhang S, Yu R, Wolfsberg TG, Meyer NP, Seaver EC, Baxevanis AD, Martín-Durán JM.   +18 more
europepmc   +1 more source