Results 241 to 250 of about 2,078,242 (303)

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source

Evolutionary and functional constraints structure human gene research visibility. [PDF]

BMC Genomics
Eswaran E, Zimmermann M, Krishnagopalan G, Ottersbach JM, Gossmann TI.   +4 more
europepmc   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Identification and drug resistance profiling of <i>Mycobacterium orygis</i> from an African elephant using whole-genome sequencing. [PDF]

Microbiol Spectr
Ghayas H, Ashraf J, Saeed N, Zaka S, Shafiq S, Farooqi J, Jabeen K, Rais A, Rizvi AI, Mustafa G, Qureshi SA, Askari Y, Salahuddin N, Ozer EA, Hasan R.   +14 more
europepmc   +1 more source

Linkage of nucleotide and functional diversity varies across gut bacteria. [PDF]

Proc Natl Acad Sci U S A
Dubinkina V, Smith BJ, Zhao C, Pino C, Pollard KS.   +4 more
europepmc   +1 more source

A reference genome sequence for the exceptionally long-lived Great Basin bristlecone pine, Pinus longaeva. [PDF]

G3 (Bethesda)
Neale DB, Zimin AV, Millar CI, McGuire PE, Hosea JA, Li E, Puiu D, Timp W, Salzberg SL.   +8 more
europepmc   +1 more source

Complete chloroplast genome sequence of the medicinal plant <i>Actaea cimicifuga</i> L. (Ranunculaceae). [PDF]

Mitochondrial DNA B Resour
Li K, Zhang H, Gao X, Wang H, Gui R, Li Y.   +5 more
europepmc   +1 more source

Mutagen-induced somatic mutation rate in primary mammalian cells in relation to maximum life span. [PDF]

Geromedicine
Heid J, Sun S, Ablaeva J, Lee M, Zhang Z, Gorbunova V, Seluanov A, Maslov AY, Vijg J.   +8 more
europepmc   +1 more source