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The Anatomy of the Human Genome

Hospital Practice, 1980
Although perhaps only 1% of the human genome has been mapped, the clinical yield is already quite impressive. This yield includes the ability to palliate some genetic diseases pharmacologically or by environmental manipulation. We can also derive critical information on which to base decisions on termination of pregnancy.
openaire   +6 more sources

From the Human Genome to the Human Proteome

Angewandte Chemie International Edition, 2014
An ultimate goal in biology is to fully understand how a cell, or even a whole organism, works. Ideally, such knowledge might be used to develop models that predict the responses of cells to specific cues or diseases. A first step towards this goal is to identify and characterize all the molecular players present in cells.
Javier Mu�oz, Albert J. R. Heck
openaire   +4 more sources

Accessing the Human Genome

Current Protocols in Human Genetics, 2002
AbstractThe majority of the sequence for the human genome is now available. Regardless of the researcher's area of interest, it is quite likely that they will want to use some aspect of this data. This unit helps researchers achieve that goal. It presents the gene models available at NCBI, the UCSC Genome Browser, and Ensembl.
Kim D. Pruitt, Deanna M. Church
openaire   +3 more sources

The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints.

Molecular Pharmacology, 2003
The superfamily of G-protein-coupled receptors (GPCRs) is very diverse in structure and function and its members are among the most pursued targets for drug development.
R. Fredriksson   +3 more
semanticscholar   +1 more source

Mapping the Human Genome

New England Journal of Medicine, 1978
The science of genetics has evolved dramatically since Mendel deduced several important principles of inheritance by observing the color of pea seeds.
openaire   +3 more sources

The Human Genome Project

Australian Journal of Forensic Sciences, 2000
The human genome project will generate significant business opportunities through better targeted treatment of disease, says Grant Sutherland. Edited highlights of his recent address to CEDA SA follow.
openaire   +3 more sources

Sequence and organization of the human mitochondrial genome

Nature, 1981
S. Anderson   +17 more
semanticscholar   +1 more source

Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

Nature Genetics, 2007
Nathaniel D. Heintzman   +14 more
semanticscholar   +1 more source

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