Unusual sequence characteristics of human chromosome 19 are conserved across 11 nonhuman primates
BMC Evolutionary Biology, 2020 Background Human chromosome 19 has many unique characteristics including gene density more than double the genome-wide average and 20 large tandemly clustered gene families.
R. Alan Harris +3 more
doaj +1 more source
The human genome browser at UCSC.
Genome Research, 2002 As vertebrate genome sequences near completion and research refocuses to their analysis, the issue of effective genome annotation display becomes critical.
W. Kent +6 more
semanticscholar +1 more source
Complete Genome Sequence of a Divergent Human Rhinovirus C Isolate from an Infant with Severe Community-Acquired Pneumonia in Colorado, USA. [PDF]
, 2017 Here, we report the genome sequence of a divergent human rhinovirus C isolate identified from an infant with a severe community-acquired respiratory infection. RNA sequencing performed on an Illumina platform identified reads aligning to human rhinovirus
DeRisi, Joseph L +4 more
core +2 more sources
Bioengineered, 2016 In the early 90s, Manfred Eigen lectured at Hoffman-La Roche and explained that a gene of 1,000 base pairs has 10605 combinations.
Christian Bach, Prabir Patra
openaire +3 more sources
Functional analysis and transcriptional output of the Göttingen minipig genome [PDF]
, 2015 In the past decade the Göttingen minipig has gained increasing recognition as animal model in pharmaceutical and safety research because it recapitulates many aspects of human physiology and metabolism.
Badi, Laura +21 more
core +3 more sources
Pan-cancer analysis of mRNA stability for decoding tumour post-transcriptional programs
Communications Biology, 2022 The role of mRNA stability in shaping the cancer transcriptome is revealed using a statistical analysis of transcriptomic data.
Gabrielle Perron +8 more
doaj +1 more source
A map of human genome variation from population-scale sequencing
Nature, 2010 The 1000 Genomes Project aims to provide a deep characterization of human genome sequence variation as a foundation for investigating the relationship between genotype and phenotype.
G. Abecasis +7 more
semanticscholar +1 more source
The Impact of Genomic Variation on Function (IGVF) Consortium [PDF]
arXiv, 2023 Our genomes influence nearly every aspect of human biology from molecular and cellular functions to phenotypes in health and disease. Human genetics studies have now associated hundreds of thousands of differences in our DNA sequence ("genomic variation") with disease risk and other phenotypes, many of which could reveal novel mechanisms of human ...
arxiv
GENCODE: The reference human genome annotation for The ENCODE Project
Genome Research, 2012 The GENCODE Consortium aims to identify all gene features in the human genome using a combination of computational analysis, manual annotation, and experimental validation.
J. Harrow +40 more
semanticscholar +1 more source
Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations [PDF]
, 2014 The HEK293 human cell lineage is widely used in cell biology and biotechnology. Here we use whole-genome resequencing of six 293 cell lines to study the dynamics of this aneuploid genome in response to the manipulations used to generate common 293 cell ...
Boone, Morgane +15 more
core +3 more sources