Results 91 to 100 of about 576,544 (290)

DNA Topoisomerase 1α Promotes Transcriptional Silencing of Transposable Elements through DNA Methylation and Histone Lysine 9 Dimethylation in Arabidopsis [PDF]

, 2014
RNA-directed DNA methylation (RdDM) and histone H3K9 dimethylation (H3K9me2) are related transcriptional silencing mechanisms that target transposable elements (TEs) and repeats to maintain genome stability in plants.
Chen, Xuemei, Dinh, Thanh Theresa, Ecker, Joseph R., Gao, Lei, Le, Brandon, Li, Dongming, Li, Shaofang, Li, Shengben, Liu, Xigang, Manavella, Pablo Andrés, O'leary, Michael, Pontes, Olga, Schmitz, Robert J., Weigel, Detlef, Zhao, Yuanyuan   +14 more
core   +5 more sources

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Isolation of a transcriptionally active element of high copy number retrotransposons in sweetpotato genome [PDF]

, 2004
Many plant retrotransposons have been characterized, but only three families (Tnt1, Tto1 and Tos17) have been demonstrated to be transpositionally competent.
Aoki, Takahiro, Kokumai, Shuhei, Matsunaga, Sachi, Suzuka, Shinya, Tahara, Makoto, Tanaka, Masaru, Yamashita, Hiroki   +6 more
core   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

Identification and co-evolution pattern of stem cell regulator miR394s and their targets among diverse plant species

BMC Evolutionary Biology, 2019
Background Micro RNAs (miRNAs), a class of small non-coding RNAs, have been implicated in various aspects of plant development. miR394 is required for shoot apical meristem organization, stem cell maintenance and abiotic stress responses in Arabidopsis ...
Ashutosh Kumar, Vibhav Gautam, Pramod Kumar, Shalini Mukherjee, Swati Verma, Ananda K. Sarkar   +5 more
doaj   +1 more source

Comprehensive Genome Analysis on the Novel Species Sphingomonas panacis DCY99(T) Reveals Insights into Iron Tolerance of Ginseng [PDF]

, 2020
Plant growth-promoting rhizobacteria play vital roles not only in plant growth, but also in reducing biotic/abiotic stress. Sphingomonas panacis DCY99(T) is isolated from soil and root of Panax ginseng with rusty root disease, characterized by raised ...
Balusamy, Sri Renukadevi, Huo, Yue, Kim, Donghyuk, Kim, Yeon-Ju, Le, Hoa Thi, Nong, Linh Khanh, Park, Joon Young, Yang, Deok Chun   +7 more
core   +1 more source

Bioinformatics Tools for Plant Genomics [PDF]

International Journal of Plant Genomics, 2008
The articles in this special issue reflect a convergence of developments in the fields of bioinformatics and plant genomics. Bioinformatics has its roots vaguely seated in the early 1980s, a time when personal computers began appearing in research laboratories and researchers began recognizing that those computers could be used as tools to organize ...
Gary R. Skuse, Chunguang Du
openaire   +3 more sources

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source

Endogenous Dionyvirus sequences are widespread in plant genomes [PDF]

, 2011
Endogenous sequences from members of the Caulimoviridae and Geminiviridae families have been identified in the genome of several plant species [1, 2].
Choisne, Nathalie, Geering, Andrew D., Quesneville, Hadi, Scalabrin, Simone, Teycheney, Pierre-Yves, Velasco, Riccardo, Vezzulli, Silvia, Zytnicki, Matthias   +7 more
core  

Genome Editing Tools in Plants [PDF]

Genes, 2017
Genome editing tools have the potential to change the genomic architecture of a genome at precise locations, with desired accuracy. These tools have been efficiently used for trait discovery and for the generation of plants with high crop yields and resistance to biotic and abiotic stresses.
Tapan Mohanta, Tufail Bashir, Abeer Hashem, Elsayed Abd_Allah, Hanhong Bae   +4 more
openaire   +2 more sources