Results 91 to 100 of about 3,521,036 (316)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

From plant genomics to plant biotechnology

, 2013
From plant genomics to -omics technologies Plant microRNAs Epigenetic control by plant Polycomb proteins: New perspectives and emerging roles in stress response Metabolite profiling for plant research The uniqueness of conifers Cryptochrome genes modulate global transcriptome of tomato Genomics of grapevine: From genomics research on model plants to ...
Poltronieri P, Burbulis N, Fogher C
openaire   +4 more sources

Distinctive expansion of potential virulence genes in the genome of the oomycete fish pathogen Saprolegnia parasitica [PDF]

, 2013
Peer ...
Marco Mammella (421707), Julio C. Vega-Arreguin (421715), Horner, N. R., van Rooyen, D., Young, S. K., Guido van den Ackerveken (5650309), Stassen, J.H.M., Javier Dieguez-Uribeondo, Berg, H., Brett M. Tyler (19744), James Christie, Young, Sarah K, Grenville-Briggs, Laura J.,, Grenville-Briggs, L., Arnaud Bottin (41550), Elzbieta Rzeszutek (421711), Andrew J. Phillips (334915), Rooyen, D., van, van den Berg, H., Stan Oome (421709), Chad Nusbaum (253636), van den Berg, Herbert, Sarah K Young, Pieter van West (205267), Christie, James, Berend Snel, Rzeszutek, Elzbieta,, Lars Löbach, Horner, N.R., Díaz-Moreno, S.M., Sarah K. Young (178826), Morris, P., Seidl, M.F., de Bruijn, I., Joshua Z. Levin (177182), Levin, Joshua Z, Sucheta Tripathy, Meijer, Harold J. G., Grenville-Briggs, L. J., Secombes, Chris J, Secombes, Chris J., Grenville-Briggs, Laura J, Carsten Russ, Oome, Stan, Wawra, Stephan, Snel, Berend, Belmonte, Rodrigo, Mammella, M., Marcia Saraiva (421712), Elodie Gaulin (40047), Rodrigo Belmonte, Dieguez-Uribeondo, J., Marco Mammella, Sara M. Díaz-Moreno (421704), Qiandong Zeng (178764), Grenville-Briggs, L.J., Lin Fan (281949), Chad Nusbaum, Dumas, B., Levin, J.Z., Andrew J Phillips, Julio C Vega-Arreguin, Horner, Neil R, Sub Theoretical Biology & Bioinformatics, Haas, B., Dep Biologie, Tyler, Brett M., Meijer, H.J., van den Ackerveken, G., Löbach, Lars, Vega-Arreguin, Julio C, Russ, C., David van Rooyen, et al., Vega-Arreguin, Julio C., Bruijn, I., de, Govers, F., van West, Pieter, van den Ackerveken, A.F.J.M., Díaz-Moreno, S., Nusbaum, Chad, Chris J Secombes, Vega-Arreguin, J. C., Sub Plant-Microbe Interactions, Gaulin, Elodie, Sykes, Sean, Meijer, H.J.G., Irene de Bruijn, Seidl, Michael F., Wawra, S., Stassen, Joost H. M., Nusbaum, C., Paul Morris, Secombes, C.J., Stassen, Joost H M, Stephan Wawra, Laura J. Grenville-Briggs (421705), Bernard Dumas, Saraiva, M., Jiang, R., Phillips, Andrew J, Belmonte, R., Grenville-Briggs, Laura J., de Bruijn, Irene, Stan Oome, Haas, B. J., Harold J. G. Meijer (227595), Saraiva, Marcia, Qiandong Zeng, Rzeszutek, E., Stassen, J. H., Young, Sarah K., Young, S.K., Neil R Horner, Phillips, A. J., Joshua Z Levin, Jiang, R. H., Theoretical Biology and Bioinformatics, Stephan Wawra (421716), Joost H. M. Stassen (221771), David van Rooyen (421710), Bulone, Vincent, Irene de Bruijn (43879), van West, P., Sucheta Tripathy (19740), Secombes, C. J., Michael F. Seidl (221772), Snel, B., Levin, Joshua Z., Michael F Seidl, Gaulin, E., Bottin, A., Joost H M Stassen, Löbach, L., West, P., van, Bernard Dumas (40050), Díaz-Moreno, Sara M., Loebach, Lars, Guido van den Ackerveken, Lars Löbach (421702), Lin Fan, Haas, Brian J, Bulone, Vincent,, Herbert van den Berg, Jiang, Rays H. Y., Sean Sykes (158441), Vincent Bulone, Seidl, Michael F, Tripathy, S., Elzbieta Rzeszutek, Rzeszutek, Elzbieta, van Rooyen, David, Tyler, Brett M, Zeng, Qiandong, Levin, J. Z., Dieguez-Uribeondo, Javier, Morris, Paul, Díaz-Moreno, S. M., Govers, Francine, Tyler, B.M., Vincent Bulone (243055), Jiang, R.H.Y., Meijer, Harold J G, Marcia Saraiva, Neil R. Horner (421706), Arnaud Bottin, Meijer, H. J., Jiang, Rays H Y, Fan, Lin, Young, Sarah, Brett M Tyler, Bulone, V., Laura J Grenville-Briggs, Jiang, R.H.I., Elodie Gaulin, Horner, N., James Christie (421703), Tyler, B. M., Christie, J., Sean Sykes, de Haas, B.J., Sara M Díaz-Moreno, Francine Govers (52155), Francine Govers, Paul Morris (421708), van den Ackerveken, Guido, West, P., Oome, S., Berend Snel (5539), Zeng, Q., Haas, B.J., Chris J. Secombes (421713), Diaz-Moreno, Sara M.,, Vega-Arreguin, J.C., Javier Dieguez-Uribeondo (421717), Haas, Brian J., Fan, L., Carsten Russ (263594), Herbert van den Berg (421714), Sykes, S., Meijer, H., Stassen, J.H., Bottin, Arnaud, Horner, Neil R., Rays H Y Jiang, Ackerveken, G., van den, Russ, Carsten, Pieter van West, Levin, J., Rooyen, D., Plant Microbe Interactions, Harold J G Meijer, Rodrigo Belmonte (421701), Mammella, Marco, Phillips, Andrew J., Phillips, A.J., Brian J. Haas (81121), Rays H. Y. Jiang (421700), Seidl, M. F., Dumas, Bernard, Tripathy, Sucheta, Díaz-Moreno, Sara M, Brian J Haas   +222 more
core   +2 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Genome sequence reveals that Pseudomonas fluorescens F113 possesses a large and diverse array of systems for rhizosphere function and host interaction [PDF]

, 2013
Background: Pseudomonas fluorescens F113 is a plant growth-promoting rhizobacterium (PGPR) isolated from the sugar-beet rhizosphere. This bacterium has been extensively studied as a model strain for genetic regulation of secondary metabolite production ...
María Sánchez-Contreras, Rivilla Palma, Rafael, Germaine, Kieran, O’Gara, Fergal, Dowling, David N., David Dowling, Sánchez-Contreras, María, Ana Navazo, Rafael Rivilla, Candela, Muriel, Martínez-Granero, Francisco, Barahona, Emma, Martinez-Granero, F., Emma Barahona, Fergal, O´Gara, Francisco Martínez-Granero, Martín, M., Redondo Nieto, Miguel, Morrissey, John P., Sánchez-Contreras, M., Candela Muriel, Barret, M., Moynihan, J., Martín Basanta, Marta, Germaine, K., Barahona, E., Navazo, A., John Morrissey, Jennifer A Moynihan, Sánchez-Contrerasa, María, Dowling, D., Moynihan, Jennifer A., Miguel Redondo-Nieto, Martín, Marta, Navazo, Ana, Morrissey, John, O\u27Gara, Fergal, Moynihan, Jennifer A, Muriel, C., Fergal O’Gara, Barret, Matthieu, Matthieu Barret, Rivilla, Rafael, Moynihan, Jennifer, Morrissey, J., Redondo-Nieto, M., Kieran Germaine, Marta Martín, Redondo-Nieto, Miguel, Rivilla, R., Muriel, Candela, Germaine, Kieran J., Dowling, David, O'Gara, Fergal   +53 more
core   +1 more source

Tomato 26S Proteasome subunit RPT4a regulates ToLCNDV transcription and activates hypersensitive response in tomato

Scientific Reports, 2016
Involvement of 26S proteasomal subunits in plant pathogen-interactions, and the roles of each subunit in independently modulating the activity of many intra- and inter-cellular regulators controlling physiological and defense responses of a plant were ...
Pranav Pankaj Sahu, Namisha Sharma, Swati Puranik, Supriya Chakraborty, Manoj Prasad   +4 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Combining extracellular matrix proteome and phosphoproteome of chickpea and meta‐analysis reveal novel proteoforms and evolutionary significance of clade‐specific wall‐associated events in plant

Plant Direct
Extracellular matrix (ECM) plays central roles in cell architecture, innate defense and cell wall integrity (CWI) signaling. During transition to multicellularity, modular domain structures of ECM proteins and proteoforms have evolved due to continuous ...
Kanika Narula, Arunima Sinha, Pooja Choudhary, Sudip Ghosh, Eman Elagamey, Archana Sharma, Atreyee Sengupta, Niranjan Chakraborty, Subhra Chakraborty   +8 more
doaj   +1 more source

Identification and co-evolution pattern of stem cell regulator miR394s and their targets among diverse plant species

BMC Evolutionary Biology, 2019
Background Micro RNAs (miRNAs), a class of small non-coding RNAs, have been implicated in various aspects of plant development. miR394 is required for shoot apical meristem organization, stem cell maintenance and abiotic stress responses in Arabidopsis ...
Ashutosh Kumar, Vibhav Gautam, Pramod Kumar, Shalini Mukherjee, Swati Verma, Ananda K. Sarkar   +5 more
doaj   +1 more source