Results 1 to 10 of about 25,444 (143)

Chromosome-level genome assembly of Trichomonas vaginalis strain IR-78 (ATCC 50138) [PDF]

open access: yesScientific Data
Trichomonas vaginalis is a flagellated protozoan parasite and the causative agent of trichomoniasis, the most prevalent non-viral sexually transmitted infection, with significant impact on public health and economy.
Mostafa Y. Abdel-Glil   +3 more
doaj   +2 more sources

Babesia gibsoni Whole-Genome Sequencing, Assembling, Annotation, and Comparative Analysis

open access: yesMicrobiology Spectrum, 2023
The intracellular protozoan parasite Babesia gibsoni infects canine erythrocytes and causes babesiosis. The hazards to animal health have increased due to the rise of B. gibsoni infections and medication resistance. However, the lack of high-quality full-
Qin Liu   +7 more
doaj   +1 more source

CRISPR/Cas9 Ribonucleoprotein-Based Genome Editing Methodology in the Marine Protozoan Parasite Perkinsus marinus

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Perkinsus marinus (Perkinsozoa), a close relative of apicomplexans, is an osmotrophic facultative intracellular marine protozoan parasite responsible for “Dermo” disease in oysters and clams.
Raghavendra Yadavalli   +11 more
doaj   +1 more source

piRNA pathway evolution beyond gonad context: Perspectives from apicomplexa and trypanosomatids

open access: yesFrontiers in Genetics, 2023
piRNAs function as genome defense mechanisms against transposable elements insertions within germ line cells. Recent studies have unraveled that piRNA pathways are not limited to germ cells as initially reckoned, but are instead also found in non-gonadal
S. Horjales   +6 more
doaj   +1 more source

Characterization of adenine phosphoribosyltransferase (APRT) activity in Trypanosoma brucei brucei: Only one of the two isoforms is kinetically active.

open access: yesPLoS Neglected Tropical Diseases, 2022
Human African Trypanosomiasis (HAT), also known as sleeping sickness, is a Neglected Tropical Disease endemic to 36 African countries, with approximately 70 million people currently at risk for infection.
Kayla Glockzin   +2 more
doaj   +1 more source

The in vivo RNA structurome of the malaria parasite Plasmodium falciparum, a protozoan with an A/U-rich transcriptome.

open access: yesPLoS ONE, 2022
Plasmodium falciparum, a protozoan parasite and causative agent of human malaria, has one of the most A/T-biased genomes sequenced to date. This may give the genome and the transcriptome unusual structural features.
Franck Dumetz   +4 more
doaj   +1 more source

CysQ of , a Protozoa, May Have Been Acquired from Bacteria by Horizontal Gene Transfer [PDF]

open access: yesGenomics & Informatics, 2012
Horizontal gene transfer (HGT) is the movement of genetic material between kingdoms and is considered to play a positive role in adaptation. Cryptosporidium parvum is a parasitic protozoan that causes an infectious disease. Its genome sequencing reported
Ji Young Lee, Sangsoo Kim
doaj   +1 more source

Are protozoan metacaspases potential parasite killers?

open access: yesParasites & Vectors, 2011
Mechanisms concerning life or death decisions in protozoan parasites are still imperfectly understood. Comparison with higher eukaryotes has led to the hypothesis that caspase-like enzymes could be involved in death pathways.
Picot Stephane   +4 more
doaj   +1 more source

Comparative analyses of parasites with a comprehensive database of genome-scale metabolic models.

open access: yesPLoS Computational Biology, 2022
Protozoan parasites cause diverse diseases with large global impacts. Research on the pathogenesis and biology of these organisms is limited by economic and experimental constraints.
Maureen A Carey   +5 more
doaj   +1 more source

Rapid, Selection-Free, High-Efficiency Genome Editing in Protozoan Parasites Using CRISPR-Cas9 Ribonucleoproteins

open access: yesmBio, 2017
Trypanosomatids (order Kinetoplastida), including the human pathogens Trypanosoma cruzi (agent of Chagas disease), Trypanosoma brucei, (African sleeping sickness), and Leishmania (leishmaniasis), affect millions of people and animals globally. T.
Lia Carolina Soares Medeiros   +8 more
doaj   +1 more source

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